Results 81 to 90 of about 3,389,680 (300)
By investigating the design and operation of low-temperature multi-effect seawater desalination (LT-MED) projects distillation equipment in power, steel, petrochemical and other industries supported by domestic, the performance evaluation indicators of ...
QI Chunhua
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Integration of Biohydrogen Production with Heat and Power Generation from Biomass Residues
The employment of renewable sources rather than fossil fuels in the production of hydrogen is an important step to achieve a sustainable hydrogen economy in the future.
W. Wukovits +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Demand Response Design of Domestic Heat Pumps
This paper proposes an emergency-based demand response (DR) controller of domestic heat pump (DHP) units based on an estimated frequency of the UK electricity in 2035.
Mohammed Jasim M. Al Essa
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
City Scale Demand Side Management in Three Different-Sized District Heating Systems
Demand side management can add flexibility to a district heating (DH) system by balancing the customer’s hourly fluctuating heat demand. The aim of this study is to analyze how different demand side management control strategies, implemented into ...
Kaisa Kontu +3 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The Forecasting of the Daily Heat Demand of the Public Sector Buildings with District Heating
This study is devoted to the increasing of the heat energy demand forecasting accuracy for district heating of the public sector buildings.
Yuliia Parfenenko +3 more
openaire +2 more sources
The laminar and turbulent regimes of a boundary layer on a flat plate are often represented with separate correlations under the assumption of a distinct “transition Reynolds number.” Average heat coefficients are then calculated by integrating across ...
Lienhard, John H, Lienhard, John H.
core +1 more source

