Results 61 to 70 of about 152,514 (266)

Flexibility Potential of Space Heating Demand Response in Buildings for District Heating Systems

Energies, 2019
Using an integrated demand-supply optimization model, this work investigates the potential for flexible space heating demand, i.e., demand response (DR), in buildings, as well as its effects on the heating demand and the operation of a district heating ...
Dmytro Romanchenko, Emil Nyholm, Mikael Odenberger, Filip Johnsson   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Heating demand – simulation and calculation

IOP Conference Series: Materials Science and Engineering, 2019
Energy efficient house is a term known very well to engineers and architects all over the world. In these times of minimizing the energy loads and negative emissions, energy efficient houses (ultra-low-energy, net-zero houses, positive houses) are one of the best ways to meet these targets.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comparison of Energy Demand for Heating and CO₂ Emissions in Urban and Rural Areas, the Case of Hajdú-Bihar County, Hungary

Buildings
Mitigating carbon dioxide emissions in the building sector is a primary global goal. This paper compares different residential buildings in urban and rural regions of Hajdú-Bihar County (Hungary).
Ferenc Kalmár, Béla Bodó, Tünde Kalmár   +2 more
doaj   +1 more source

Predictive Optimization of the Heat Demand in Buildings at the City Level

Applied Sciences, 2019
Easily adaptable indoor temperature and heat demand models were applied in the predictive optimization of the heat demand at the city level to improve energy efficiency in heating.
Petri Hietaharju, Mika Ruusunen, Kauko Leiviskä, Marko Paavola   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Establishment of performance evaluation indicators for low-temperature multi-effect seawater desalination equipment and analysis of typical engineering datas

Gongye shui chuli
By investigating the design and operation of low-temperature multi-effect seawater desalination (LT-MED) projects distillation equipment in power, steel, petrochemical and other industries supported by domestic, the performance evaluation indicators of ...
QI Chunhua
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Integration of Biohydrogen Production with Heat and Power Generation from Biomass Residues

Chemical Engineering Transactions, 2013
The employment of renewable sources rather than fossil fuels in the production of hydrogen is an important step to achieve a sustainable hydrogen economy in the future.
W. Wukovits, A. Drljo, E. Hilby, A. Friedl   +3 more
doaj   +1 more source