Results 91 to 100 of about 2,847,525 (288)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Domestic Heat Pump System With Solar Thermal Collectors as Heat Source and Annual Ice Storage [PDF]
Aim of this paper is a theoretical and experimental investigation of a domestic heating system with heat pump using solar thermal collectors as the only heat source.
Gschwend, Andreas, Bertsch, Stefan S.
core +1 more source
Inverse Problem for Parabolic Equation with Dynamic Integral Boundary Conditions
We study a one-dimensional heat equation with dynamic integral boundary conditions together with an inverse problem for recovering an unknown boundary source from interior temperature measurements.
Miglena N. Koleva, Lubin G. Vulkov
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
A Quantum Algorithm for Multidimensional Partial Differential Equations with Practical Case Studies
Partial differential equations (PDEs) play a central role in scientific and engineering analysis, with applications spanning fluid dynamics, heat and mass transfer, electromagnetism, quantum mechanics, and financial modeling, where they are used to ...
Manu Chaudhary +14 more
doaj +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
A Comparative Study of The Heat Equation and The Fractional Heat Equation
Theclassicalheatequationhasservedasacornerstoneofdiffusiontheoryandpartialdifferentialequationssince Fourier's seminal work in the early nineteenth century. Its elegant mathematical structure and predictive power in modeling thermal conduction and diffusion processes have made it indispensable across physics, engineering, and applied mathematics ...
openaire +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
The Heat Equation is a partial differential equation that describes the distribution of heat over a period of time. The heat equation is important in many fields of Mathematics.
Xu, Ethan
core +1 more source

