Results 81 to 90 of about 257,535 (310)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
A dynamical sampling scheme for solving a generalized heat equation
, 2018 We study an initial value problem for a generalized version of the heat equation, involving time/space variant coefficients, and fairly unknown initial conditions.
Alshehri, Mohammed Nasser A.
core
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
On a boundary value problem for the nonhomogeneous heat equation in an angular domain
Вестник КазНУ. Серия математика, механика, информатика, 2017 Due to the fact that the results find theoretical and practical applications, great attention is paid to the study of boundary value problems for parabolic equations.
M. A. Sadybekov, M. G. Yergaliyev
doaj
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Beyond the classical strong maximum principle: Sign-changing forcing term and flat solutions
Advances in Nonlinear AnalysisWe show that the classical strong maximum principle, concerning positive supersolutions of linear elliptic equations vanishing on the boundary of the domain can be extended, under suitable conditions, to the case in which the forcing term is sign ...
Díaz Jesús Ildefonso +1 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Proceedings of the International Conference on Applied Innovations in ITIn this article, we use the variational approach as a regularization tool to solve the initial value problem which appear in a heat partial differential equation.
H.K. Al-Mahdawi +5 more
doaj +1 more source
A Novel Numerical Treatment to One Dimensional Heat and Wave Equations with Second Order Accuracy [PDF]
Computational Algorithms and Numerical DimensionsNumerical solutions to partial differential equations (PDEs) play a vital role in modeling complex physical phenomena across scientific computing and engineering disciplines.
Muhammad Abid, Muhammad Shahid
doaj +1 more source