Results 41 to 50 of about 214,382 (263)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Some optimal control problems of heat equations with weighted controls
Boundary Value Problems, 2017 In this paper, the time and norm optimal control problems of controlled heat equations with a weight function are considered. For the time optimal problems, we study the following two cases: one is for equations with multi-domain control under null ...
Shufang Liu, Dandan Liu, Guoqi Wang
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Semilinear heat equation with singular terms
Electronic Journal of Qualitative Theory of Differential Equations, 2022 The main goal of this paper is to analyze the existence and nonexistence as well as the regularity of positive solutions for the following initial parabolic problem $$ \begin{cases} \partial_tu-\Delta u=\displaystyle\mu\frac{u}{|x|^{2}}+\frac{f}{u ...
Mohamed Mahmoud Ould Khatri +1 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Tracking Controllability for the Heat Equation
IEEE Transactions on Automatic ControlWe study the tracking or sidewise controllability of the heat equation. More precisely, we seek for controls that, acting on part of the boundary of the domain where the heat process evolves, aim to assure that the normal trace or flux on the complementary set tracks a given trajectory. The dual equivalent observability problem is identified.
Jon Asier Bárcena-Petisco +1 more
openaire +4 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
MathematicsIn this paper, two-dimensional (2D) heat equations on disjoint rectangles are considered. The solutions are connected by interface Robin’s-type internal conditions.
Miglena N. Koleva, Lubin G. Vulkov
doaj +1 more source
Solutions to viscous Burgers equations with time dependent source term
Electronic Journal of Differential Equations, 2021 We study the existence and uniqueness of weak solutions for a Cauchy problem of a viscous Burgers equation with a time dependent reaction term involving Dirac measure.
Satyanarayana Engu +2 more
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