Results 51 to 60 of about 236,875 (344)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Response Surface Method for Design of Room Air Conditioner Heat Exchangers with Decreasing Tube Diameter

open access: yesZhileng xuebao, 2011
The response surface method is applied to design the heat exchanger with decreasing tube diameter, for the traditional design methods are not suitable for the optimization of the performance and cost of heat exchanger simultaneously.
Wu Zhaoguo   +5 more
doaj   +2 more sources

Test and Analysis of the Heat Exchanger for Small Ocean Thermal Energy Power Generation Devices

open access: yesEnergies, 2023
The application of ocean thermal energy conversion is an effective method to extend underwater vehicles’ running times and operating ranges, and the solid–liquid phase transition of the phase change material (PCM) in the heat exchanger is a key process ...
Xiao Wu, Xiangnan Wang, Bingzhen Wang
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Pengaruh Kecepatan Fluida Terhadap Nilai Efektivitas pada Heat Exchanger Tipe Shell and Tube (The Effect of Fluid Flow Velocity to Determine the Effectiveness of Heat Exchanger Shell and Tube) [PDF]

open access: yes, 2016
As a device to exchange heat from hot fluid to colder fluid, a heat exchanger is supposed to have high effectiveness. Theoretically, the increase of fluid rate would increase the effectiveness.
PUSPITA DEWI, MEIKE
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Influence of metallic porous microlayer on pressure drop and heat transfer of stainless steel plate heat exchanger [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +2 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Research on Heat Exchanger of Gas Hydrate Mud Cooling System

open access: yesZhileng xuebao, 2017
The heat exchanger of the gas hydrate mud cooling system is very critical to the exploitation of gas hydrate. Based on the occurrence characteristics of gas hydrate, the study focused on the effect of different kinds of heat exchanger to the original gas
Zhao Shuai   +5 more
doaj  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

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