Results 41 to 50 of about 63,706 (311)

Thermal-hydraulic characteristics and optimization of a liquid-to-suction triple-tube heat exchanger

open access: yesCase Studies in Thermal Engineering, 2020
The highly effective heat-transfer characteristic of a triple-tube heat exchanger was applied to the liquid-to-suction heat exchanger of an R410A refrigerator.
Vo Tuyen   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Thermodynamic Analysis of One Kind of Single-stage with Expender and Four Kinds of Two-stage Transcritical Carbon Dioxide Refrigeration Cycle

open access: yesZhileng xuebao, 2016
The performances of single-stage transcritical CO2 cycle with expander, transcritical CO2 two-stage cycle without intermediate heat exchanger, transcritical CO2 two-stage cycle with intermediate heat exchanger, transcritical CO2 two-stage & primary ...
Sun Zhili, Ma Yitai
doaj   +2 more sources

Comparative Temperature Distribution Characteristics and Thermal Efficiency of a Conventional Rice Cooker (CRC) and a Vapor Chamber Rice Cooker (VRC)

open access: yesWalailak Journal of Science and Technology, 2016
A conventional rice cooker (CRC) and a vapor chamber rice cooker (VRC) were designed and constructed in equal mass, capacity, material, depth and inside diameter.
Viroj LIMKAISANG, Wasan SRIMUANG
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Experimental and numerical investigation of heat transfer and flow characteristics for tractor heat exchanger (radiator)

open access: yesمجلة النهرين للعلوم الهندسية, 2017
An experimental and numerical study was carried out to investigate heat transfer and flow characteristics through the tractor heat exchanger (radiator). The engine of the tractor is Diesel (compression ignition) engine type.
Kadhim F. Nasir
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Membrane and plastic heat exchangers performance [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2005
The performance of a membrane-based heat exchanger utilizing porous paper as the heat and moisture transfer media is presented. The measured performance is compared with a plastic film heat exchanger.
Masud Behnia   +2 more
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

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