Results 51 to 60 of about 179,550 (294)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Response Surface Method for Design of Room Air Conditioner Heat Exchangers with Decreasing Tube Diameter

open access: yesZhileng xuebao, 2011
The response surface method is applied to design the heat exchanger with decreasing tube diameter, for the traditional design methods are not suitable for the optimization of the performance and cost of heat exchanger simultaneously.
Wu Zhaoguo   +5 more
doaj   +2 more sources

Influence of metallic porous microlayer on pressure drop and heat transfer of stainless steel plate heat exchanger [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +2 more
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Flow Visualisation Studies On Wall Mounted Pitot Type Intake With Splitter Plate [PDF]

open access: yes, 1991
Flow Visualisation Studies Employing Schlieren/Shadowgraph Technique And -Simple Oil Flow Technique Were Carried Out On A Simple Pitot Type Of 1-Btake With Splitter Plate Mounted On Base Plate In The NAL 0 .3m Tunnel .
Narasimhaswamy, KN, Ramaswamy, MA
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Pengaruh Kecepatan Fluida Terhadap Nilai Efektivitas pada Heat Exchanger Tipe Shell and Tube (The Effect of Fluid Flow Velocity to Determine the Effectiveness of Heat Exchanger Shell and Tube) [PDF]

open access: yes, 2016
As a device to exchange heat from hot fluid to colder fluid, a heat exchanger is supposed to have high effectiveness. Theoretically, the increase of fluid rate would increase the effectiveness.
PUSPITA DEWI, MEIKE
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Research on Heat Exchanger of Gas Hydrate Mud Cooling System

open access: yesZhileng xuebao, 2017
The heat exchanger of the gas hydrate mud cooling system is very critical to the exploitation of gas hydrate. Based on the occurrence characteristics of gas hydrate, the study focused on the effect of different kinds of heat exchanger to the original gas
Zhao Shuai   +5 more
doaj  

An Evaluation of Heat Exchangers Using System Information and PEC [PDF]

open access: yes, 2000
This report describes analyses aimed at integrating component optimization and system design by developing heat-exchanger performance evaluation criteria (PEC) that account for the system-level performance impacts of heat exchanger design. It builds on
Bullard, C.W., Jacobi, A.M., Pira, J.V.
core  

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