Results 91 to 100 of about 123,959 (281)

A Case of Legionnaires' Disease Manifesting as Heat Exhaustion. [PDF]

Cureus, 2023
Malik MA, Shaukat F, Malik A, Kaifee S, Eid M.   +4 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Analysis of heat stroke and heat exhaustion cases in EudraVigilance pharmacovigilance database. [PDF]

Eur J Clin Pharmacol, 2023
Gamboa L, Lafuente AS, Morera-Herreras T, Garcia M, Aguirre C, Lertxundi U.   +5 more
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

A Case of Heat Exhaustion Masquerading as ST-Elevation Myocardial Infarction. [PDF]

Cureus, 2022
Egaimi M, Seo H, Bashir S.
europepmc   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Creep fatigue life prediction for engine hot section materials (isotropic): Two year update [PDF]

, 1984
Requirements for increased durability of gas turbine hot section components have placed a greater degree of importance on accurate structural analysis and life prediction.
Moreno, V.
core   +1 more source

On some strong ratio limit theorems for heat kernels

, 2010
We study strong ratio limit properties of the quotients of the heat kernels of subcritical and critical operators which are defined on a noncompact Riemannian manifold.Comment: 16 pages.
Fraas, M., Krejcirik, D., Pinchover, Y.
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Ectodermal Dysplasia Presenting as Heat Exhaustion in an Adolescent Boy. [PDF]

Cureus, 2021
Guntreddi G, Vasudevan Nair J, Nirujogi SP.   +2 more
europepmc   +1 more source