Results 81 to 90 of about 123,959 (281)

The gut-liver axis plays a limited role in mediating the liver’s heat susceptibility of Chinese giant salamander

open access: yesBMC Genomics
The Chinese giant salamander (CGS, Andrias davidianus), a flagship amphibian species, is highly vulnerable to high temperatures, posing a significant threat under future climate change.
Runliang Zhai   +6 more
doaj   +1 more source

Creatine and glycerol hyperhydration in trained subjects prior to exercise in the heat. [PDF]

open access: yes, 2007
The authors examined the effects of combined creatine (Cr) and glycerol (Gly) supplementation on responses to exercise in the heat. Subjects (N = 24) were matched for body mass and assigned to either a Cr or placebo (Pl) group. Twice daily during two 7-d
Easton, Chris   +2 more
core  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

An asymptotic dimension for metric spaces, and the 0-th Novikov-Shubin invariant

open access: yes, 2001
A nonnegative number d_infinity, called asymptotic dimension, is associated with any metric space. Such number detects the asymptotic properties of the space (being zero on bounded metric spaces), fulfills the properties of a dimension, and is invariant ...
Guido, Daniele, Isola, Tommaso
core  

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

Factors Related To Heat Strain In Tough-Making Industry Workers In Kotabumi Selatan District, North Lampung District

open access: yesProfessional Health Journal
Tofu industry workers are a group vulnerable to heat strain due to high heat exposure during work. Heat strains can cause serious health problems such as heat stroke, heat exhaustion, and heat cramps.
Dony Mahendra   +2 more
doaj   +1 more source

Body temperature regulation: Sasang typology-based perspective

open access: yesIntegrative Medicine Research, 2015
Global warming induces a dramatic elevation of heat-related morbidity and mortality worldwide. Individual variation of heat stress vulnerability depends on various factors such as age, gender, living area and conditions, health status, and individual ...
Duong Duc Pham, Chae Hun Leem
doaj   +1 more source

Novikov-Shubin invariants and asymptotic dimensions for open manifolds

open access: yes, 1998
The Novikov-Shubin numbers are defined for open manifolds with bounded geometry, the Gamma-trace of Atiyah being replaced by a semicontinuous semifinite trace on the C*-algebra of almost local operators.
Guido, Daniele, Isola, Tommaso
core   +3 more sources

The r-Process in Supersonic Neutrino-Driven Winds: The Roll of Wind Termination Shock

open access: yes, 2007
Recent hydrodynamic studies of core-collapse supernovae imply that the neutrino-heated ejecta from a nascent neutron star develops to supersonic outflows.
Akira Ohnishi   +9 more
core   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

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