Results 31 to 40 of about 503,620 (268)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Monitoring the mental workload of construction workers is effective in detecting risky subjects because cognitive overload may threaten their safety.
Shiyi He +5 more
doaj +1 more source
Intermittent heat exposure and thirst in rats
Adequate water intake, supporting both cardiovascular function and evaporative cooling, is a critical factor in mitigating the effects of heat waves, which are expected to increase with global warming. However, the regulation of water intake during periods of intermittent heat exposure is not well understood.
Barney, Christopher C., Kuhrt, David M.
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
ObjectivesThis research aims to analyze how exposure to fine particulate matter (PM2.5) and ambient heat during pregnancy increases the risk of congenital hydronephrosis (CH) in newborns.MethodsA case–control study was conducted to investigate the ...
ZhiMeng Huang +8 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
BackgroundIt is unclear if there is any combined effect of air pollutants and non-optimal temperature on metabolic syndrome, or any molecular mechanisms of related signaling pathways in the process, which requires urgent systematic research.
Biao WU +7 more
doaj +1 more source
Arrays Formation of Zinc Oxide Nano-Objects with Varying Morphology for Sensor Applications
The regularities and features of the formation of arrays of zinc oxide nano-objects with varying morphology are determined by CO2 laser processing with intensification of diffusion processes in the solid state of Cu–Zn metallic materials which are ...
Serguei P. Murzin, Nikolay L. Kazanskiy
doaj +1 more source
Investigation of kidney function changes in sea salt workers during harvest season in Thailand
Background. The Thai government has been developing its Eastern Economic Corridor (EEC), which spans three provinces, with the aim of improving connections with other Asian nations. Since this strategic development, the number of trucks, private car, and
Titaporn Luangwilai +2 more
doaj +1 more source

