Results 91 to 100 of about 4,882,110 (280)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Thermal performance of shell-and-tube polymeric hollow fiber heat exchangers as oil coolers

open access: yesCase Studies in Thermal Engineering
Motor oil must be appropriately treated in motors, and aluminum plate heat exchangers are used to cool it. An aluminum heat exchanger is an additional part of the oil treatment module, which increases its size and weight.
Ilja Astrouski   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

The harmonic map heat flow from surfaces [PDF]

open access: yes
We present a study of the harmonic map heat flow of Eells and Sampson in the case that the domain manifold is a surface. Particular emphasis has been placed on the singularities which may occur, as described by Struwe, and the analysis of the flow ...
Topping, Peter
core  

Analytical considerations of flow boiling heat transfer in metal-foam filled tubes [PDF]

open access: yes, 2012
Flow boiling in metal-foam filled tube was analytically investigated based on a modified microstructure model, an original boiling heat transfer model and fin analysis for metal foams.
Zhao, Changying   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Particle size distribution measurement based on ultrasonic attenuation spectra using burst superposed wave

open access: yesResults in Physics, 2019
In the characterization of particle size distribution (PSD) using ultrasonic attenuation method, the spectrum characteristics such as bandwidth or the number of frequencies is of great significance.
Nan Jia, Ming-xu Su, Xiao-shu Cai
doaj   +1 more source

Contextuality in Anomalous Heat Flow

open access: yesPRX Quantum
In classical thermodynamics, heat must spontaneously flow from hot to cold systems. In quantum thermodynamics, the same law applies when considering multipartite product thermal states evolving unitarily. If initial correlations are present, anomalous heat flow can happen, temporarily making cold thermal states colder and hot ...
Naim E. Comar   +4 more
openaire   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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