Results 71 to 80 of about 2,060,902 (303)

Pseudo-Leidenfrost phenomenon of low surface tension droplet induced by external aerodynamic field

AIP Advances, 2023
Droplet regulation has significant application potential in many fields; however, conventional controlling methods make it difficult to effectively control low surface tension droplets.
Jinzhu Xu, Li Jia, Xinyuan Liu, Chao Dang, Yi Ding   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Influence of spheroidal particle shape on particle size characterization by multi-wavelength light extinction method

Results in Physics, 2018
In order to improve the applicability, spheroidal particles are substituted for the spherical particles in the traditional modeling of multi-wavelength light extinction method.
Yi Zhou, Jun Chen, Hui-nan Yang, Tan Li, Ming-xu Su   +4 more
doaj   +1 more source

Prototype Boiling Ketupat Type of Batch Study of Heat Transfer Coefficient Into Condensor [PDF]

, 2013
So far for producing ketupat done using boiling system open by using a regular steamer so much heat loss occurs due to his high consumption of fuel, to reduce the fuel consumption of the writers tried to make a prototype of a batch type boiling ketupat ...
Erlangga, R. (Reli)
core   +1 more source

Cooling Performance of a Novel Circulatory Flow Concentric Multi-Channel Heat Sink with Nanofluids [PDF]

, 2020
Heat rejection from electronic devices such as processors necessitates a high heat removal rate. The present study focuses on liquid-cooled novel heat sink geometry made from four channels (width 4 mm and depth 3.5 mm) configured in a concentric shape ...
Ahmadi, Mohammad H., Jilte, Ravindra, Kalamkar, Vilas, Kumar, Ravinder, Mosavi, Amir (Dr)   +4 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Experimental and numerical investigation on forced convection in circular tubes with nanofluids [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Colla, L, Fedele, L, Manca, O, Marinelli, L, Nardini, S   +5 more
core  

Thermal analysis and optimization of a heat regenerator composed of two coupled moving bed heat exchangers [PDF]

, 2008
This work presents a study to optimize the performance of a heat regenerator composed by two coupled moving bed heat exchangers (MBHE). A MBHE is used to recover heat, from a hot gas stream, and the other one is used to preheat an air stream.
Almendros Ibáñez, José Antonio, Ruiz-Rivas Hernando, Ulpiano, Santana Santana, Domingo José, Soria Verdugo, Antonio   +3 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source