Results 81 to 90 of about 2,060,902 (303)

Research on Active Flow Control Method of NACA0012 Airfoil with Traveling Wave Structure [PDF]

open access: yesJournal of Applied Fluid Mechanics
Traveling wave is an innovative active flow control technique that can remarkably mitigate flow separation. This paper employs numerical simulation to examine how traveling wave structures affect the NACA0012 airfoil.
Q. Dai   +4 more
doaj   +1 more source

Duality and Heat flow

open access: yesAdvances in Mathematics
We reveal the relation between the Legendre transform of convex functions and heat flow evolution, and how it applies to the functional Blaschke-Santalo inequality. We also describe local maximizers in this inequality.
Cordero-Erausquin, Dario   +3 more
openaire   +4 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Heat Flow Density in a region with Hot Springs- NW of Portugal and SW of Galicia (Spain) [PDF]

open access: yes, 2019
Heat flow density and temperature are studied in a region characterized by a very marked topography and the existence of thermal springs. The work was made with results obtained in studies involving heat sources in the region due to the decay of ...
Duque, Maria Rosa
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Melting dynamics of large ice balls in a turbulent swirling flow

open access: yes, 2013
We study the melting dynamics of large ice balls in a turbulent von Karman flow at very high Reynolds number. Using an optical shadowgraphy setup, we record the time evolution of particle sizes.
Bianchi A. M.   +6 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Probe measures characteristics of hot gas stream [PDF]

open access: yes, 1965
Shielded, tubular flow calorimeter operated by valve position measures characteristics of a hot gas stream of unknown composition. Measurements of mass flow density and total heat content per unit mass, total heat content per unit mass only, and pitot ...

core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Pressure drop across micro-pin heat sinks under boiling conditions [PDF]

open access: yes, 2009
Two-phase pressure drop was studied in four different micro pin fin heat sinks. Micro pin fin heat sinks used in the current studies were operated under boiling conditions using water and R-123 as working fluids.
Keskinoz, Mehmet   +5 more
core  

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