Results 111 to 120 of about 678,372 (307)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Local heat flux and energy loss in a 2D vibrated granular gas

, 2004
We performed event-driven simulations of a two-dimensional granular gas between two vibrating walls and directly measured the local heat flux and energy dissipation rate in the stationary state.
Annette Zippelius, Olaf Herbst, Peter Müller, S. Chapman   +3 more
core   +1 more source

Conductive heat loss in simulated outdoor settings: a preliminary experimental human study

International Journal of Emergency Medicine
Background Little is known about the nature and magnitude of conductive heat loss in outdoor environments. Although manikin studies provide reproducible and consistent data, they may not fully reflect all aspects of human physiological responses.
Tomasz Sanak, Mateusz Putowski, Stanisław Krzeptowski-Sabała, Janusz Pobędza, Paweł Walczak, Konrad Mendrala, Tomasz Darocha, Sylweriusz Kosiński   +7 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

A Study of Evaporation Heat Transfer Coefficient Correlations at Low Heat and Mass Fluxes for Pure Refrigerants and Refrigerant Mixtures [PDF]

, 1993
An average R12 refrigerant correlation has been developed for the mass flux range of 25-100 kg/m2-s and the heat flux range of 2-10 kW/m2. Refrigerant mixtures of 80% R22/lO% R141b and 65% R22/35% R123 have also been tested over asjrniJar range of ...
Newell, T.A., Smith, M.K., Wattelet, J.P.   +2 more
core  

Magneto-thermoplasmonics: from theory to applications

, 2018
We review recent theoretical developments on the nanoscale radiative heat transfer in magneto-optical many-particle systems. We discuss in detail the circular heat flux, the giant magneto-resistance effect, the persistent heat current, and the thermal ...
Ben-Abdallah, Philippe, Biehs, Svend-Age, Messina, Riccardo, Ott, Annika   +3 more
core   +3 more sources

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source