Results 81 to 90 of about 4,691,836 (302)

Heat and Mass Transfer [PDF]

open access: yes, 2019
Heat and mass transfer is the core science for many industrial processes as well as technical and scientific devices. Automotive, aerospace, power generation (both by conventional and renewable energies), industrial equipment and rotating machinery ...

core   +1 more source

Generalized Heat Kernel Signatures.

open access: yesJ. WSCG, 2011
In this work we propose a generalization of the Heat Kernel Signature (HKS). The HKS is a point signature derived from the heat kernel of the Laplace-Beltrami operator of a surface. In the theory of exterior calculus on a Riemannian manifold, the Laplace-Beltrami operator of a surface is a special case of the Hodge Laplacian which acts on r-forms, i. e.
Zobel, Valentin   +2 more
openaire   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Tables for solution of the heat-conduction equation with a time-dependent heating rate [PDF]

open access: yes, 1962
Tables are presented for the solution of the transient onedimensional heat flow in a solid body of constant material properties with the heating rate at one boundary dependent on time. These tables allow convenient and rapid estimation of the temperature
Bergles A. E.
core  

Heat conduction in cylinders: Entropy generation and mathematical inequalities

open access: yes, 2018
We examine the entropy generation regarding its magnitude and the limit as time tends to infinity and apply the second law of thermodynamics to develop mathematical inequalities with heat conduction in adiabatic cylinders.
Xiaowei Tian   +3 more
core   +1 more source

Marangoni convection in a double diffusive binary fluid with temperature dependent viscosity, Coriolis force and internal heat generation [PDF]

open access: yes, 2019
A steady Marangoni convection in a horizontal double diffusive binary fluid is considered. Present study investigated the effects of temperature dependent viscosity, Coriolis force and internal heat generation to the onset of convection.
Mohd Mokhtar, Nor Fadzillah   +2 more
core   +1 more source

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