Results 41 to 50 of about 1,082,311 (314)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Influence of Heat Input on Microstructure and Mechanical Properties of Gas Tungsten Arc Welded HSLA S500MC Steel Joints

open access: yesMetals, 2022
High-strength low alloy (HSLA) S500MC steel is widely used for chassis components, structural parts, and pressure vessels. In this study, the effects of heat input during automatic gas tungsten arc welding (GTAW) on microstructure and mechanical ...
Kianoosh Kornokar   +6 more
doaj   +1 more source

Laser Hardening Using Step Functional Heat Input

open access: yesBulletin of JSME, 1983
In this paper, a method of laser hardening is proposed, where CW CO2 laser beam is used as a step functional heat input instead of a moving heat source. This method is applied to the plane surfaces of cylinders as an example. The hardening process is analyzed theoretically using the theory of heat conduction and considering the following four important
Etsuji OHMURA   +2 more
openaire   +2 more sources

SPAN - Terminal sterilization process analysis program [PDF]

open access: yes, 1969
Computer program, SPAN, measures the dry heat thermal sterilization process applied to a planetary capsule and calculates the time required for heat application, steady state conditions, and cooling.

core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effect of CMT Welding Heat Input on Microstructure and Properties of 2A14 Aluminum Alloy Joint

open access: yesMetals, 2022
Cold metal transfer (CMT) welding is an attractive welding technology for thin sheet aluminum alloys because of its low heat input, arc stability and spatter-free behavior during the welding process.
Yili Zhao   +4 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Heat Input Influence on the Fatigue Life of Welds from Steel S460MC

open access: yesMetals, 2020
Fine-grained steels belong to the progressive materials, which are increasingly used in the production of welded structures subjected to both static and dynamic loads.
Jaromir Moravec   +3 more
doaj   +1 more source

The unlikely Carnot efficiency

open access: yes, 2014
The efficiency of an heat engine is traditionally defined as the ratio of its average output work over its average input heat. Its highest possible value was discovered by Carnot in 1824 and is a cornerstone concept in thermodynamics.
Broeck, Christian Van den   +3 more
core   +1 more source

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