Results 41 to 50 of about 176,436 (256)

Heat Load Estimator for Smoothing Pulsed Heat Loads on Supercritical Helium Loops

Physics Procedia, 2015
AbstractSuperconducting magnets for fusion are subjected to large variations of heat loads due to cycling operation of tokamaks. The cryogenic system shall operate smoothly to extract the pulsed heat loads by circulating supercritical helium into the coils and structures.
Hoa, C., Lagier, B., Rousset, B., Bonnay, P., Michel, Frederic   +4 more
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Shifts and plasticity of plant leaf mass per area and leaf size among slope aspects in a subalpine meadow

Ecology and Evolution, 2021
The composition of vegetation on a slope frequently changes substantially owing to the different micro‐environments of various slope aspects. To understand how the slope aspect affects the vegetation changes, we examined the variations in leaf mass per ...
Xin’e Li, Xiaoyu Song, Jun Zhao, Haifeng Lu, Cheng Qian, Xin Zhao   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Investigation of the Flow Distribution in Parallel Evaporating Branches of a Separate Heat Pipe

Zhileng xuebao, 2019
A two-phase computational fluid dynamics (CFD) simulation of seven parallel evaporating branches in a separate heat pipe with two different heat loads was conducted and the flow distribution characteristics was assessed in the study.
Luo Yun, Wang Wen, Zuo Qiaolin, Ye Cheng
doaj  

Effects of high heat load conditions on body weight, feed intake, temperature, and respiration of Dorper, Katahdin, and St. Croix sheep

Journal of Applied Animal Research, 2019
Forty-six Dorper, 46 Katahdin, and 43 St. Croix female sheep from four regions of the USA were used to evaluate responses to high heat load index (HLI) conditions.
Dereje Tadesse, Ryszard Puchala, Terry A. Gipson, Arthur L. Goetsch   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Dairy cow behaviour and physical activity as indicators of heat stress

Italian Journal of Animal Science
Heat stress in dairy cattle is a major concern in modern dairy farming. Potentially, techniques developed in the field of precision livestock farming that monitor cow behaviour could enable an early detection of heat stress.
L. M. C. Leliveld, D. Lovarelli, E. Riva, G. Provolo   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source