Results 41 to 50 of about 2,796,382 (285)
The addition of heat pump electricity load profiles to GB electricity demand: Evidence from a heat pump field trial [PDF]
Previous studies on the effect of mass uptake of heat pumps on the capability of local or national electricity grids have relied on modelling or small datasets to create the aggregated heat pump load profile.
Summerfield, A +47 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Study On Annual Performance Of Room Air Conditioners Under Partial Load Condition [PDF]
Because of the moderate climate of Japan, most of the air conditioners (A/Cs) used are split-type A/Cs and can provide both heating and cooling during the year.
Hihara, Eiji, Horie, Hayato
core +1 more source
The primary objective of this report is to provide a convenient, consistent and accurate method of calculating heating and cooling loads and to enable the designer to select systems that meet the requirement for efficient utilization and are also responsive to environmental needs.
Junaid Hussain, Gaffar, Syed Abdul
openaire +1 more source
Thermal quadrupole method with internal heat sources [PDF]
A new method based on the thermal quadrupoles technique for heat transfer modelling in multilayered slabs with heat sources is proposed. Classical thermal quadrupoles use hyperbolic functions and numerical problems occur according to the argument value ...
A. Kusiak +21 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

