Results 101 to 110 of about 2,098,712 (312)

High-Intensity Synchrotron Radiation Effects [PDF]

open access: yes, 2016
Various effects of intense synchrotron radiation on the performance of particle accelerators, especially for storage rings, are discussed. Following a brief introduction to synchrotron radiation, the basic concepts of heat load, gas load, electron ...
Suetsugu, Y.
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Variational Characterizations of Local Entropy and Heat Regularization in Deep Learning

open access: yes, 2019
The aim of this paper is to provide new theoretical and computational understanding on two loss regularizations employed in deep learning, known as local entropy and heat regularization.
Kaplan, Zach   +2 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Dynamic building envelopes [PDF]

open access: yes, 2008
Chris Leung explains his recent research into deployable external insulation: dynamic facades which use paraffin wax and passive environmental technology to move between open and closed states and allow what has until now often been mutually ...
Gage, S.A., Leung, C.
core  

Quantum Coherence and Closed Timelike Curves

open access: yes, 1995
Various calculations of the $S$ matrix have shown that it seems to be non unitary for interacting fields when there are closed timelike curves. It is argued that this is because there is loss of quantum coherence caused by the fact that part of the ...
A. Anderson   +13 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Thermionic triode generates ac power [PDF]

open access: yes, 1970
Electrostatic grid controls conduction cycle of thermionic diode to convert low dc output voltages to high ac power without undesirable power loss. An ac voltage applied to the grid of this new thermionic triode enables it to convert heat directly into ...
Kniazzeh, A. G. F., Scharz, F. C.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Experimental study of flow distribution with circumferential manifolds [PDF]

open access: yes, 1972
Water flow test results on fluid flow distribution and pressure loss in curved manifolds with tangential or radial entry are reported. Manifolds were studied both as inlet and outlet manifolds. Manifolds can be used for boilers and/or heat exchangers for
Dittrich, R. T.
core   +1 more source

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