Results 81 to 90 of about 2,098,712 (312)

IMPROVING THE EFFICIENCY OF THE HEATING SYSTEM FOR PUBLIC BUILDINGS INFRASTRUCTURE IN THE CONTEXT OF DNURT

open access: yesNauka ta progres transportu, 2016
Purpose. The paper analyses the possibility and terms of increasing the efficiency of heating and ventilation systems of public buildings at the present stage of development and the specific climatic conditions of Ukraine.
O. M. Pshinko   +3 more
doaj   +1 more source

Recent Progress in Hydrogen Flammability Prediction for the Safe Energy Systems

open access: yesEnergies, 2020
Many countries consider hydrogen as a promising energy source to resolve the energy challenges over the global climate change. However, the potential of hydrogen explosions remains a technical issue to embrace hydrogen as an alternate solution since the ...
Joongoo Jeon, Sung Joong Kim
doaj   +1 more source

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

open access: yes, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Development of On-Board In-Cylinder Gas Flow Model for Heat Loss Estimation of Diesel Engines

open access: yesJIRAE (International Journal of Industrial Research and Applied Engineering), 2018
Diesel engines have been demanded to further increase the thermal efficiency through precise engine control under transient driving conditions, especially, it is essential to optimize the fuel injection timing and quantity cycle-by-cycle. Conventionally,
Mitsuhisa Ichiyanagi   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Development of On-board Polytropic Index Prediction Model for Injection Timing Optimization of Diesel Engines

open access: yesJIRAE (International Journal of Industrial Research and Applied Engineering), 2018
Diesel engines are required to reduce exhaust emissions during real-world operations. In this regard, a new control concept called model-based control has been explored.
Mitsuhisa Ichiyanagi   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mathematical Modeling of Heat Transfer and Energy Efficiency in Above-Ground Outdoor Pools

open access: yesAppliedMath
Above-ground outdoor swimming pools are increasingly popular due to their affordability and ease of installation, yet maintaining optimal water temperature under variable climate conditions remains challenging.
Łukasz Dziubiński   +2 more
doaj   +1 more source

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