Results 91 to 100 of about 687,172 (315)

Modelling of Flow and Heat Transfer in Spent Fuel Cooling Ponds [PDF]

, 2015
With increased interest in Nuclear power generation and the issues of storing legacy fuels being apparent there is a real need to understand the heat transfer mechanisms involved in storing spent fuel within water filled cooling ponds.
Hasan, Reaz, Tudor, Jenna, Ramadan, Ahmed   +2 more
core  

Application of the Discrete Ordinates Method to Compute Radiant Heat Loss in a Diesel Engine [PDF]

, 1997
A three-dimensional model for computing flows, sprays, and combustion in internal combustion engines is modified to include radiant heat loss. Radiant heat loss is computed by solving the radiative transport equation using a discrete ordinates ...
J. Abraham, MAGI, Vinicio
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Numerical Study of Convective Heat Transfer for Flat Unglazed Transpired Solar Collectors [PDF]

, 2012
Convective heat transfer coefficients (CHTC) for flat unglazed transpired solar collectors have been computed using high-resolution 3-dimensional steady RANS CFD simulations.
Li, Siwei, Karava, Panagiota
core   +1 more source

Development of On-Board In-Cylinder Gas Flow Model for Heat Loss Estimation of Diesel Engines

JIRAE (International Journal of Industrial Research and Applied Engineering), 2018
Diesel engines have been demanded to further increase the thermal efficiency through precise engine control under transient driving conditions, especially, it is essential to optimize the fuel injection timing and quantity cycle-by-cycle. Conventionally,
Mitsuhisa Ichiyanagi, Kazuki Kojima, Hayao Joji, Hiroki Matsui, Takashi Suzuki   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Thermal physiology of selected African ungulates with emphasis on the physical properties of the pelage [PDF]

, 1981
The ungulates include some of the largest land animals and, in consequence, they cannot avoid climatic stress as do small mammals. A great deal of information concerning the physiology of thermoregulation in domestic ungulates is available but relatively
Hofmeyr, Margaretha Delina
core  

Geographic and temporal variations in turbulent heat loss from lakes: a global analysis across 45 lakes [PDF]

, 2018
Heat fluxes at the lake surface play an integral part in determining the energy budget and thermal structure in lakes, including regulating how lakes respond to climate change.
Karjalainen, Juha,, Woolway, R Iestyn, Sean Kelly, Kallio, Kari, Jonna Kuha, Hamilton, David P, Lepistoe, Ahti, de Eyto, E., Pierson, Don, Laas, A., Lepistö, A., de Eyto, Elvira, Kuha, J., Laas, Alo,, Merchant, Christopher J., Healey, N.C., Woolway, R. Iestyn,, Merchant, Christopher J, Rusak, James A.,, Kari Kallio, Hamilton, David P.,, Lenters, J.D., Lepistoe, Ahti,, Woolway, R, Kelly, Sean,, Christopher J. Merchant, Rusak, J.A., Hamilton, David, Piet Verburg, Woolway, R.I., Pierson, Don,, Merchant, Christopher J.,, Rusak, James, Healey, Nathan C, Lepisto, Ahti, David P. Hamilton, Healey, Nathan C.,, Juha Karjalainen, Verburg, Piet, Kelly, Sean, Rusak, James A., Kallio, K., Alo Laas, et al., Hamilton, David P., Lenters, John D, Karjalainen, J., Verburg, Piet,, Jones, Ian D.,, Lenters, John D., Don Pierson, Rusak, James A, James A. Rusak, Merchant, C.J., Brookes, Justin, Lenters, John D.,, Nathan C. Healey, Brookes, Justin,, Kallio, Kari,, Karjalainen, Juha, Justin Brookes, Brookes, J., Merchant, Christopher, de Eyto, Elvira,, Hook, Simon, Kuha, Jonna, Kuha, Jonna,, Simon Hook, Jones, I.D., Kelly, S., Hamilton, D.P., Elvira de Eyto, Jones, Ian D., Verburg, P., Hook, Simon,, Healey, Nathan C., John D. Lenters, Ahti Lepistö, Lenters, John, Laas, Alo, Woolway, R. Iestyn, Healey, Nathan, R. Iestyn Woolway, Jones, Ian D, Ian D. Jones, Hook, S., Pierson, D.   +86 more
core   +1 more source

Development of On-board Polytropic Index Prediction Model for Injection Timing Optimization of Diesel Engines

JIRAE (International Journal of Industrial Research and Applied Engineering), 2018
Diesel engines are required to reduce exhaust emissions during real-world operations. In this regard, a new control concept called model-based control has been explored.
Mitsuhisa Ichiyanagi, Hayao Joji, Hiroki Matsui, Emir Yilmaz, Takashi Suzuki   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source