Results 71 to 80 of about 4,602,806 (291)

Heat-loss effects on the chaotic behavior of cellular premixed flames generated by intrinsic instability

open access: yesJournal of Thermal Science and Technology, 2007
Heat-loss effects on the chaotic behavior of cellular premixed flames generated by intrinsic instability were studied by two-dimensional unsteady calculations of reactive flows based on the compressible Navier-Stokes equation.
Amornrat KAEWPRADAP, Satoshi KADOWAKI
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Optimisation of Heat Loss through Ventilation for Residential Buildings

open access: yesAtmosphere, 2018
This study presents the results of research on heat loss from various types of residential buildings through ventilation systems. Experimental research was done to analyse the effectiveness of ventilation systems of different types and determine the ...
Dariusz Suszanowicz
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

EFFECT OF USING INTERNAL PACKAGING MATERIALS FOR NEW BUILDING WALLS ON HEATING LOAD

open access: yesJournal of Engineering and Sustainable Development, 2017
Experimental and theoretical investigation of three types of internal packaging materials(PVC, MDF, Gypsum board) for the residential building was carried out in the present work, to reduce the heating load in winter. Experiments were carried out at the
Hassan Kareem Abdullah   +1 more
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Studi Numerik Pengaruh Kecepatan Angin Terhadap Critical Radius dan Distribusi Temperatur Pada Pipa Uap

open access: yesJurnal Teknik ITS, 2015
Umumnya transmisi uap panas menggunakan pipa dengan diameter yang besar. Pada transmisi uap panas tersebut, kehilangan panas dan penurunan temperatur selalu terjadi.
Eka Arisma Setyo Nugroho   +1 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

GENERAL MODEL OF RADIATIVE AND CONVECTIVE HEAT TRANSFER IN BUILDINGS: PART I: ALGEBRAIC MODEL OF RADIATIVE HEAT TRANSFER

open access: yesActa Polytechnica, 2019
Radiative heat transfer is the most effective mechanism of energy transport inside buildings. One of the methods capable of computing the radiative heat transport is based on the system of algebraic equations.
Tomáš Ficker
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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