Results 111 to 120 of about 465,173 (296)

Detection of shared antigenic determinants between Mycobacterium leprae heat shock protein 65 and human heat shock protein 60

Hansenologia Internationalis, 2003
In these studies, it was investigated whether M. leprae and man share antigenic determinants which may be located on Heat Shock Proteins (HSPs), and which may be responsible for tissue destruction.
David Njoo, Ricardo.V.P. Hu, Bhupendra Tank, Arend.H.J. Kolk, Angela Kooy, René Kant, Bernard Naafs   +6 more
doaj   +1 more source

Heat shock proteins

, 2001
Heat shock proteins are three families of proteins classified according to their molecular weight (27 kDa, 70 kDa and 90 kDa). These well conserved proteins are responsible for the protection of other polypeptides within the cell after external stress. In animals, overexpression of these proteins is observed following different situations ranging from ...
David, J.C., Grongnet, Jean-François
openaire   +3 more sources

3D Printing of Stretchable, Compressible and Conductive Porous Polyurethane for Soft Robotics

Advanced Materials Technologies, EarlyView.
A 3D‐printable porous dopamine‐polyurethane acrylate elastomer results in conductive, stretchable, and compressible structures that can be metallized in situ through catechol‐mediated silver reduction. The resulting material function as both compliant soft robot with a and strain sensors without complex assemblies, enabling fully 3D‐printed soft ...
Ouriel Bliah, Konstantin Sakharov, Pooi See Lee, Shlomo Magdassi   +3 more
wiley   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line

Journal of Inflammation, 2011
Poly (ADP-ribose) polymerase-1 (PARP-1) is a highly conserved multifunctional enzyme, and its catalytic activity is stimulated by DNA breaks. The activation of PARP-1 and subsequent depletion of nicotinamide adenine dinucleotide (NAD+) and adenosine ...
Zingarelli Basilia, Gefter Julia V, Sjodin Hanna, Aneja Rajesh K, Delude Russell L   +4 more
doaj   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Differential gene expression studies on HsfA4d, HsfB2a and ClpD1/HSP100 during heat stress in the rice varieties N22 and Co51

Electronic Journal of Plant Breeding, 2020
In the present investigation, differential expression of two transcription factor genes (HsfA4d and HsfB2a) and a heat shock protein (ClpD1/HSP100) was evaluated in the rice varieties N22 and Co 51 using qRT-PCR.
Rishima Maheendran, V. Soundarrajan, N. M. Manikanda Boopathi, R. Gnanam, V. Geethalakshmi and P. Meenakshisundaram
doaj   +1 more source

Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells [PDF]

, 2018
Molecular chaperones are central to cellular protein homeostasis. In mammals, protein misfolding diseases and aging cause inflammation and progressive tissue loss, in correlation with the accumulation of toxic protein aggregates and the defective ...
Finka, Andrija, Goloubinoff, Pierre, Mattoo, Rayees   +2 more
core  

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source