Heat Shock Protein 60 in Cardiovascular Physiology and Diseases [PDF]
Frontiers in Molecular Biosciences, 2020 Heat shock protein 60 (HSP60) is a highly conserved protein abundantly expressed in both prokaryotic and eukaryotic cells. In mammals, HSP60 has been primarily considered to reside in the mitochondria, where HSP60 and HSP10 form a complex and facilitate ...
Yaoyun Duan +5 more
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Heat Shock Protein 60 in Hepatocellular Carcinoma: Insights and Perspectives [PDF]
Frontiers in Molecular Biosciences, 2020 Heat shock protein 60 (HSP60) is a mitochondrial chaperone that is implicated in physiological and pathological processes. For instance, it contributes to protein folding and stability, translocation of mitochondrial proteins, and apoptosis.
Abdullah Hoter +3 more
doaj +6 more sources
The Heat Shock Protein 60 and Pap1 Participate in the Sporothrix schenckii-Host Interaction [PDF]
Journal of Fungi, 2021 Sporothrixschenckii is one of the etiological agents of sporotrichosis, a worldwide-distributed subcutaneous mycosis. Its cell wall contains a glycoconjugate composed of rhamnose, mannose, glucuronic acid, and proteins, named peptidorhamnomannan, which ...
Laura C. García-Carnero +7 more
doaj +2 more sources
Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor [PDF]
Cell Communication and Signaling, 2020 Adiponectin, an adipokine produced and secreted by adipocytes, is involved in regulating the development and progression of insulin resistance, diabetes, and diabetic complications.
Deling Zhang +9 more
doaj +2 more sources
Detection of Chlamydial Heat Shock Protein 60 and 10 Antibody among Female Infertility [PDF]
Journal of Global Infectious DiseasesIntroduction: Of the many sexually transmitted pathogens, Chlamydia trachomatis is increasingly being associated with long-term sequelae such as infertility, apart from causing genital tract infections.
Gopi Dhivya +5 more
doaj +2 more sources
Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia [PDF]
Cells, 2022 Currently, no commercially available drugs have the ability to reverse cachexia or counteract muscle wasting and the loss of lean mass. Here, we report the methodology used to develop Physiactisome—a conditioned medium released by heat shock protein 60 ...
Valentina Di Felice +14 more
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Mechanistic study of heat shock protein 60-mediated apoptosis in DF-1 cells [PDF]
Poultry Science: Heat shock proteins (HSP) are a group of highly conserved molecular chaperones found in various organisms and have been associated with tumorigenesis, tumor progression, and metastasis.
Yanlan Li, Shengliang Cao, Yubao Li
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Role of heat shock protein 60 in primed and naïve states of human pluripotent stem cells. [PDF]
PLoS ONE, 2022 Human pluripotent stem cells (hPSCs) exist in at least two distinct states in mammals: naïve pluripotency that represents several molecular characteristics in pre-implantation epiblast and primed pluripotency that corresponds to cells poised for ...
Hong Seo Choi +3 more
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Clinicopathologic significance of heat shock protein 60 as a survival predictor in breast carcinoma [PDF]
Frontiers in OncologyBackgroundWhile Heat Shock Protein 60 (HSP60) has been linked to human tumor, its clinic significance specifically in breast carcinoma is unclear. This investigation aims to retrospectively evaluate how HSP60 protein levels relate to survival outcomes ...
Qing Wang +3 more
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Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure. [PDF]
Cell Death Differ, 2020 To maintain healthy mitochondrial enzyme content and function, mitochondria possess a complex protein quality control system, which is composed of different endogenous sets of chaperones and proteases.
Fan F +13 more
europepmc +3 more sources