Results 41 to 50 of about 347,980 (289)
BMC Cardiovascular Disorders, 2006 Background There have been suggestions of an association between Chlamydia pneumoniae, chlamydial heat shock protein (Ch-hsp) 60 and human heat shock protein (h-hsp) 60 infection sero-status and development of secondary cardiovascular events.
Twardella Dorothee +3 more
doaj +1 more source
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats [PDF]
, 2013 Background: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear ...
Csonka, Csaba +10 more
core +3 more sources
Heat Shock Protein-60 and Risk for Cardiovascular Disease
Current Pharmaceutical Design, 2011 Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. There is growing evidence that molecular chaperones, many of which are heat shock proteins HSPs, are involved in CVD pathogenesis. In this review we focus on HSP60, the human mitochondrial chaperone that also displays extramitochondrial and extracellular functions ...
Manfredi, Rizzo +7 more
openaire +4 more sources
Tolerization against atherosclerosis using heat shock protein 60. [PDF]
Cell Stress Chaperones, 2016 Atherosclerosis is a chronic inflammatory disease of the artery wall, and both innate and adaptive immunity play important roles in the pathogenesis of this disease. In several experimental and human experiments of early atherosclerotic lesions, it has been shown that the first pathogenic event in atherogenesis is intimal infiltration of T cells at ...
Wick C.
europepmc +4 more sources
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
The 60-kDa heat shock protein modulates allograft rejection [PDF]
Proceedings of the National Academy of Sciences, 1999 Allograft rejection is a process of immune reactivity triggered by foreign transplantation antigens. We now demonstrate that the 60-kDa heat shock protein (hsp60), a molecule that is identical in the donor and the recipient, can regulate allograft immunity. In wild-type mice, hsp60 expression was greatly enhanced in allografts being rejected.
O S, Birk +8 more
openaire +2 more sources
Late onset distal hereditary motor neuropathy type IIB (dHMN IIB) – case reports
Aktualności Neurologiczne, 2018 Distal hereditary motor neuropathies are a heterogeneous group of rare, genetically determined neuromuscular disorders. Distal hereditary motor neuropathy type IIB is an autosomal dominant disorder, and the onset of symptoms is observed in adulthood ...
Mateusz Spławski +2 more
doaj +1 more source
Circulating heat shock protein 60 levels are elevated in HIV patients and are reduced by anti-retroviral therapy. [PDF]
PLoS ONE, 2012 Circulating heat shock protein 60 (Hsp60) and heat shock protein 10 (Hsp10) have been associated with pro- and anti-inflammatory activity, respectively. To determine whether these heat shock proteins might be associated with the immune activation seen in
Itaru Anraku +5 more
doaj +1 more source
Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection. [PDF]
PLoS ONE, 2016 The genus Paracoccidioides comprises species of dimorphic fungi that cause paracoccidioidomycosis (PCM), a systemic disease prevalent in Latin America. Here, we investigated whether administration of native 60-kDa heat shock protein of P.
Fabrício Freitas Fernandes +8 more
doaj +1 more source
Heat shock proteins in health and disease: therapeutic targets or therapeutic agents? [PDF]
, 2001 For many years, heat shock or stress proteins have been regarded as intracellular molecules that have a range of housekeeping and cytoprotective functions, only being released into the extracellular environment in pathological situations such as necrotic
Pockley, A.G.
core +1 more source