Results 41 to 50 of about 177,270 (246)

Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection. [PDF]

PLoS ONE, 2016
The genus Paracoccidioides comprises species of dimorphic fungi that cause paracoccidioidomycosis (PCM), a systemic disease prevalent in Latin America. Here, we investigated whether administration of native 60-kDa heat shock protein of P.
Fabrício Freitas Fernandes, Leandro Licursi de Oliveira, Taise Natali Landgraf, Gabriela Peron, Marcelo Vieira Costa, Arlete A M Coelho-Castelo, Vânia L D Bonato, Maria-Cristina Roque-Barreira, Ademilson Panunto-Castelo   +8 more
doaj   +1 more source

Role of Heat Shock Protein 65/60 in the Pathogenesis of Atherosclerosis [PDF]

International Archives of Allergy and Immunology, 2009
Investigations in rabbits and humans have provided experimental evidence that autoimmune reactions play a major role in the initial stages of the development of atherosclerosis. These involve the infiltration of the arterial intima with T cells reacting with heat shock protein (hsp) 65/60 and the occurrence of anti-hsp 65/60 antibodies.
G, Wick, R, Kleindienst, G, Schett, A, Amberger, Q, Xu   +4 more
openaire   +2 more sources

Stable Reference Gene Selection for RT-qPCR Analysis in Nonviruliferous and Viruliferous Frankliniella occidentalis. [PDF]

PLoS ONE, 2015
Reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) is a reliable technique for measuring and evaluating gene expression during variable biological processes.
Chunxiao Yang, Hui Li, Huipeng Pan, Yabin Ma, Deyong Zhang, Yong Liu, Zhanhong Zhang, Changying Zheng, Dong Chu   +8 more
doaj   +1 more source

Suppression of Heat Shock Protein-70 by Ceramide in Heat Shock-induced HL-60 Cell Apoptosis [PDF]

Journal of Biological Chemistry, 2000
Ceramide has emerged as a mediator of cell growth, differentiation, and apoptosis in many biological systems. Many kinds of stresses are reported to induce apoptosis with an increase of ceramide generation. Here we showed that the intracellular ceramide levels increased in parallel with heat shock (HS)-induced apoptosis in an intensity- and time ...
T, Kondo, T, Matsuda, M, Tashima, H, Umehara, N, Domae, K, Yokoyama, T, Uchiyama, T, Okazaki   +7 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Toxoplasma gondii Strains: Bioinformatic Analysis of Heat shock protein 60 Gene in Experimentally Infected Mice [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2019
Background and study aim: There is a need for more detailed characterisation of T. gondii strains to determine the level of genetic variability which is useful in effective diagnosis, treatment and control of toxoplasmosis.
Mona Mattar, Rania Hamza, Ghada Fathy, Tahani Farag, Howayda Moawad, Enas Elbahaie, Abdelnasser Madboli, Ashraf Barakat   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Unveiling the impact of SUMOylation at K298 site of heat shock factor 1 on glioblastoma malignant progression

Neoplasia: An International Journal for Oncology Research
Background: Glioblastoma (GBM) poses a significant medical challenge due to its aggressive nature and poor prognosis. Mitochondrial unfolded protein response (UPRmt) and the heat shock factor 1 (HSF1) pathway play crucial roles in GBM pathogenesis.
Xiang Li, Zongqi Wang, Bixi Gao, Kun Dai, Jiang Wu, Kecheng Shen, Guangzhao Li, Xiaowang Niu, Xin Wu, Longyuan Li, Haitao Shen, Haiying Li, Zhengquan Yu, Zhong Wang, Gang Chen   +14 more
doaj   +1 more source

Relevance of Helicobacter pylori infection in Egyptian multiple sclerosis patients

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background Multiple sclerosis (MS) is an autoimmune demyelinating disorder. The etiology of MS remains unknown exactly. Helicobacter pylori heat shock proteins were suggested as a potential trigger of immune system causing MS.
Steven Emil Gerges, Taha Kamel Alosh, Salma Hamed Khalil, Mona Mokhtar Waheed El Din   +3 more
doaj   +1 more source