Results 41 to 50 of about 171,704 (286)
Heat Shock Protein-60 and Risk for Cardiovascular Disease
Current Pharmaceutical Design, 2011 Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. There is growing evidence that molecular chaperones, many of which are heat shock proteins HSPs, are involved in CVD pathogenesis. In this review we focus on HSP60, the human mitochondrial chaperone that also displays extramitochondrial and extracellular functions ...
Manfredi, Rizzo +7 more
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Extracellular Heat Shock Protein 60, Cardiac Myocytes, and Apoptosis [PDF]
Circulation Research, 2009 Rationale: Previously, we have found that changes in the location of intracellular heat shock protein (HSP)60 are associated with apoptosis. HSP60 has been reported to be a ligand of Toll-like receptor (TLR)-4.
Se-Chan, Kim +8 more
openaire +2 more sources
BMC Cardiovascular Disorders, 2006 Background There have been suggestions of an association between Chlamydia pneumoniae, chlamydial heat shock protein (Ch-hsp) 60 and human heat shock protein (h-hsp) 60 infection sero-status and development of secondary cardiovascular events.
Twardella Dorothee +3 more
doaj +1 more source
The 60-kDa heat shock protein modulates allograft rejection [PDF]
Proceedings of the National Academy of Sciences, 1999 Allograft rejection is a process of immune reactivity triggered by foreign transplantation antigens. We now demonstrate that the 60-kDa heat shock protein (hsp60), a molecule that is identical in the donor and the recipient, can regulate allograft immunity. In wild-type mice, hsp60 expression was greatly enhanced in allografts being rejected.
O S, Birk +8 more
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Late onset distal hereditary motor neuropathy type IIB (dHMN IIB) – case reports
Aktualności Neurologiczne, 2018 Distal hereditary motor neuropathies are a heterogeneous group of rare, genetically determined neuromuscular disorders. Distal hereditary motor neuropathy type IIB is an autosomal dominant disorder, and the onset of symptoms is observed in adulthood ...
Mateusz Spławski +2 more
doaj +1 more source
, 2005 BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis.
Mandal, K +20 more
core +1 more source
Role of Heat Shock Protein 65/60 in the Pathogenesis of Atherosclerosis [PDF]
International Archives of Allergy and Immunology, 2009 Investigations in rabbits and humans have provided experimental evidence that autoimmune reactions play a major role in the initial stages of the development of atherosclerosis. These involve the infiltration of the arterial intima with T cells reacting with heat shock protein (hsp) 65/60 and the occurrence of anti-hsp 65/60 antibodies.
G, Wick +4 more
openaire +2 more sources
Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection. [PDF]
PLoS ONE, 2016 The genus Paracoccidioides comprises species of dimorphic fungi that cause paracoccidioidomycosis (PCM), a systemic disease prevalent in Latin America. Here, we investigated whether administration of native 60-kDa heat shock protein of P.
Fabrício Freitas Fernandes +8 more
doaj +1 more source
Cytosolic Heat Shock Protein 60, Apoptosis, and Myocardial Injury [PDF]
Circulation, 2002 Background — Heat shock proteins (HSPs) are well known for their ability to “protect” the structure and function of native macromolecules, particularly as they traffic across membranes.
S R, Kirchhoff, S, Gupta, A A, Knowlton
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Stable Reference Gene Selection for RT-qPCR Analysis in Nonviruliferous and Viruliferous Frankliniella occidentalis. [PDF]
PLoS ONE, 2015 Reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) is a reliable technique for measuring and evaluating gene expression during variable biological processes.
Chunxiao Yang +8 more
doaj +1 more source