Results 91 to 100 of about 352,389 (290)

Small but crucial : the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans [PDF]

, 2012
Peer reviewedPublisher ...
A Dereeper, A Hartl, A Hubel, A Shonhai, A Walther, A Yamamoto, AA Sanchez, AF Ram, AJ Brown, AJP Brown, Alistair J. P. Brown, AM Gillum, AM Murad, B Eisman, B Enjalbert, B Enjalbert, B Enjalbert, B Hube, B Wachtler, Bernhard Hube, C Askew, C Csank, C Fradin, C Gancedo, C Schuller, CA Kumamoto, CC Sheth, CF Urban, CJ Nobile, D Harcus, D Ribatti, DA Smith, DL Richie, DM Arana, Duncan Wilson, E Roman, EA Craig, F Estruch, F Moller, F Narberhaus, FA Castro, FC Odds, FJ Alvarez-Peral, François L. Mayer, G Butler, GJ Caspers, GR Stewart, H Liu, H Park, H Ruis, H Wisplinghoff, H Yamaguchi, HJ Lo, HT Rupniak, ID Jacobsen, ID Jacobsen, Ilse D. Jacobsen, Iryna M. Bohovych, J Buchner, J Fan, J Ferrer, J Horwitz, JC Arguelles, JD Malhotra, JN Sun, JP Burnie, JR Glover, K Richter, K Sales, K Zakikhany, KD Metzler, KL Meibom, L Petko, LE Cowen, LL Hoyer, LY Chiang, M Chaput, M Haslbeck, M Haslbeck, M Haslbeck, M Lis, M Martinez-Esparza, M Martinez-Esparza, M Ramsdale, M Ruhnke, M Werner-Washburne, MA Ramirez, MC Lorenz, MC Lorenz, MG Marcu, N Benaroudj, N Jaya, N Santoro, NA Gow, NA Gow, Neeraj Chauhan, O Zaragoza, O Zaragoza, P Ratnakar, P Van Dijck, Pedro Miramón, PK Sorger, PK Sorger, PL Fidel Jr, PW Piper, QT Phan, QT Phan, R Van Montfort, RA Calderone, RA Monge, RB Wilson, RE Susek, RS Shapiro, S Diamant, S Diamant, S Gola, S Hohmann, S Lindquist, S Lindquist, S Nicholls, S Nicholls, S Thewes, S Welker, SG Filler, SH Kaufmann, Silvia Slesiona, SJ Eyles, SL Elson, TF de Koning-Ward, VE Chester, Y Dubaquie, Y Zhu, YL Tsai, YL Tsai   +133 more
core   +4 more sources

Heat shock protein 60 induces inflammatory mediators in mouse adipocytes

FEBS Letters, 2008
Adipocytes represent an important cellular source of inflammatory mediators. However, the signals for the induction of proinflammatory adipocyte activities are largely unknown. Here, we demonstrate that heat shock protein (Hsp) 60, a potent stimulator of innate immunity, induces the release of the inflammatory mediators interleukin‐6, CXCL1 and ...
Gülden, Elke, Mollérus, Sina, Brüggemann, Jutta, Burkart, Volker, Habich, Christiane   +4 more
openaire   +2 more sources

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

β-Caryophyllene as a Potential Protective Agent Against Myocardial Injury: The Role of Toll-Like Receptors

Molecules, 2019
Myocardial infarction (MI) remains one of the major causes of mortality around the world. A possible mechanism involved in myocardial infarction is the engagement of Toll-like receptors (TLRs).
Nancy S. Younis, Maged E. Mohamed
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Heat shock proteins and the cellular response to osmotic stress [PDF]

, 2000
In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X., Grünbein, Rita, Lugmayr, Karin, Neuhofer, Wolfgang   +3 more
core   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Bioinformatics and Molecular Characterization Study of the HSP60 Gene of Pomacea canaliculata (Lamarck, 1822)

مجلة ديالى للعلوم الزراعية
A freshwater Pomacea canaliculata snail is widely spread across countries, including Iraq, and has the possibility for habitat alterations and lives under unusual conditions.
Sarmad Awad Mozan AL-Asadi, Noor J. A. Jouda, Sahar M. A. AL-Mothafer, Muhammed J. Al-Emara, Ali AL-Ali   +4 more
doaj   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source