Hawaiian Picture‐Winged Drosophila Exhibit Adaptive Population Divergence along a Narrow Climatic Gradient on Hawaii Island [PDF]
1. Anthropogenic influences on global processes and climatic conditions are increasingly affecting ecosystems throughout the world. 2. Hawaii Island’s native ecosystems are well studied and local long‐term climatic trends well documented, making these ...
Bellinger, M. Renee +2 more
core +2 more sources
Background: Self-antigens such as heat shock protein 60 (HSP 60) have recently been implicated in the periodontal disease pathogenesis. There is scant evidence regarding HSP 60 levels in circulation and saliva following periodontal disease and its ...
R Ramya Nethravathy +3 more
doaj +1 more source
Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins [PDF]
The plant hormone auxin is central in many aspects of plant development. Previous studies have implicated the ubiquitin-ligase SCFTIR1 and the AUX/IAA proteins in auxin response.
Estelle, M. +4 more
core +1 more source
BACKGROUND AND OBJECTIVE: The bacteria begin to synthesize heat shock proteins (hsp) when facing elevated temperatures. Some of the hsps recognized during infection by host immune system.
R Rajabnia, +4 more
doaj
Heat stress induces both apoptosis and necrosis in normal human osteoblasts without heat shock protein-60 (HSP60) release [PDF]
Thermal trauma can irreversibly damage bone cells; however, the mechanisms by which thermal trauma affects thebone microenvironment are poorly characterized.
Kanokwan Charoonpatrapong-Panyayong +2 more
doaj
Developmental regulation of the heat shock response by nuclear transport factor karyopherin-α3 [PDF]
During early stages of Drosophila development the heat-shock response cannot be induced. It is reasoned that the adverse effects on cell cycle and cell growth brought about by Hsp70 induction must outweigh the beneficial aspects of Hsp70 induction in the
Chen, Tianxin +3 more
core
A Novel Therapeutic Strategy for the Treatment of Glioma, Combining Chemical and Molecular Targeting of Hsp90a [PDF]
Hsp90α's vital role in tumour survival and progression, together with its highly inducible expression profile in gliomas and its absence in normal tissue and cell lines validates it as a therapeutic target for glioma.
Adi Mehta +55 more
core +2 more sources
Aging cellular networks: chaperones as major participants
We increasingly rely on the network approach to understand the complexity of cellular functions. Chaperones (heat shock proteins) are key "networkers", which have among their functions to sequester and repair damaged protein. In order to link the network
Agoston +56 more
core +1 more source
Detection of antihuman HSP60 antibody in patients with type 1 diabetes
Background and Objective: Type I diabetes is a chronic disorder of pancreas. This disorder occurs as a result of autoimmune destruction of insulin producing beta-cells. Long duration before the onset of clinical symptoms, the autoimmune reactions develop.
A Mostafa Zadeh +4 more
doaj
Cloning, molecular analysis and epitopics prediction of a new chaperone GroEL Brucella melitensis antigen [PDF]
Objective(s):Brucellosis is a well-known domestic animal infectious disease, which is caused by Brucella bacterium. GroEL antigen increases Brucella survival and is one of the major antigens that stimulates the immune system.
Mohammad Hadi Sekhavati +5 more
doaj

