Results 131 to 140 of about 137,496 (252)

Heat shock protein 90 inhibition attenuates inflammation in models of atopic dermatitis: a novel mechanism of action. [PDF]

Front Immunol, 2023
Ben Abdallah H, Bregnhøj A, Ghatnekar G, Iversen L, Johansen C.   +4 more
europepmc   +1 more source

Heat shock protein 90 (Hsp90) [PDF]

Science-Business eXchange, 2008
openaire   +3 more sources

Polycationic Peptide Engineering of Phage Endolysins Expands Host Range and Enhances Antibacterial and Antibiofilm Activities Against Bacillus Species

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Farhat Ansari, Tarushi, Vandan Nagar
wiley   +1 more source

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation. [PDF]

Int J Mol Med
Wu K, Xu W, You Q, Guo R, Feng J, Zhang C, Wu W.   +6 more
europepmc   +1 more source

Revisiting the Carbon Footprint of Single‐Use Technologies in Biomanufacturing: A Bottom‐Up Analysis Reveals a Paradigm Shift

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The biopharmaceutical industry increasingly relies on single‐use technologies (SUT) for operational flexibility. For a long time, SUT was considered more sustainable than stainless‐steel (SST) systems due to water and energy savings. This study re‐evaluates this paradigm via a detailed bottom‐up analysis of the SUT carbon footprint at the 2000 
Jan Reiners, Katharina Bruno‐Thakur, Daina Romeo, Weronika Kuśmierczyk, Ferdinand Stückler   +4 more
wiley   +1 more source

Serum heat shock protein 90 alpha levels in mild and severe preeclampsia. [PDF]

Rev Assoc Med Bras (1992)
Canbolat KH, Açıkgöz AS, Gök K, Tüten A, Kaya B, Gayretli TK, Özçil MD, Malik E, Güralp O.   +8 more
europepmc   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Heat shock protein 90 chaperone activity is required for hepatitis A virus replication. [PDF]

J Virol
Li Y, Zheng X, Xie L, Kapustina M, Shirasaki T, Yonish B, Chen X, Hirai-Yuki A, Nagata N, Suzuki R, Isogawa M, Vogt MR, Muramatsu M, Lemon SM.   +13 more
europepmc   +1 more source

Enhanced Inhibition of Amyloid Formation by Heat Shock Protein 90 Immobilized on Nanoparticles. [PDF]

ACS Chem Neurosci, 2023
Rodríguez-Ramos A, González JA, Fanarraga ML.   +2 more
europepmc   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source