Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Diagnostic Efficacy of Heat Shock Protein 90 Alpha (HSP90α), Neuron-Specific Enolase (NSE), and Carcinoembryonic Antigen (CEA) Serum Biomarkers in the Diagnosis of Lung Cancer. [PDF]
Jain M +5 more
europepmc +1 more source
Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Expression of Heat Shock Protein 90 Genes Induced by High Temperature Mediated Sensitivity of <i>Aphis glycines</i> Matsumura (Hemiptera: Aphididae) to Insecticides. [PDF]
Han X +5 more
europepmc +1 more source
Clathrate hydrate crystallization
Abstract Clathrate hydrate crystallization has been an area of interest to chemical engineers from the point of view of crystal structure, thermophysical properties, phase equilibria, kinetics, industrial applications, and environmental (climate change) implications.
Peter Englezos
wiley +1 more source
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas +5 more
wiley +1 more source
Potential role of heat shock protein 90 (Hsp90) in HIV uncoating
Stoddart Cheryl A, Joshi Pheroze
doaj +1 more source
Heat stress-induced heat shock protein 90 alpha family class A member 1 upregulation stabilizes yes-associated protein through ubiquitination inhibition to boost hepatic cancer radiofrequency hyperthermia resistance. [PDF]
Bao Z, Jiang Y, Liang W, Zhang D, Guo L.
europepmc +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Advanced Glycation End-Product-Modified Heat Shock Protein 90 May Be Associated with Urinary Stones. [PDF]
Takata T +6 more
europepmc +1 more source

