Results 231 to 240 of about 309,378 (343)

Targeting heat shock protein 90 with usnic acid relieves immune suppression via aryl hydrocarbon receptor-mediated mechanisms in lung cancer. [PDF]

Mol Biomed
Varlı M, Ahn EJ, Bhosle SR, Moon KS, Ha HH, Kim H.   +5 more
europepmc   +1 more source

Inhibition of heat-shock protein 90 reduces Ebola virus replication

, 2010
Darci R. Smith, Sarah McCarthy, Andrew Chrovian, Gene G. Olinger, Andrea Stossel, Thomas W. Geisbert, Lisa E. Hensley, John H. Connor   +7 more
openalex   +2 more sources

In vivo evidence for the generation of a glucocorticoid receptor-heat shock protein-90 complex incapable of binding hormone by the calmodulin antagonist phenoxybenzamine. [PDF]

, 1996
Y. Ning, Estaban Sánchez
openalex   +1 more source

Data from Heat Shock Protein 90 Inhibition Depletes LATS1 and LATS2, Two Regulators of the Mammalian Hippo Tumor Suppressor Pathway

, 2023
Catherine J. Huntoon, Monica D. Nye, Liyi Geng, Kevin L. Peterson, Karen S. Flatten, Paul Haluska, Scott H. Kaufmann, Larry M. Karnitz   +7 more
openalex   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

The role of heat shock protein 90 in idiopathic pulmonary fibrosis: state of the art. [PDF]

Eur Respir Rev
Monteleone G, Cameli P, Bonella F.
europepmc   +1 more source

Heat shock protein 90 (Hsp90) inhibitor STA-9090 (Ganetespib) ameliorates inflammation in a mouse model of atopic dermatitis. [PDF]

Cell Stress Chaperones, 2023
Sitko K, Starke M, Tukaj S.
europepmc   +1 more source

Expression of recombinant human casein kinase II and recombinant heat shock protein 90 in Escherichia coli and characterization of their interactions.

, 1994
Yongyu Shi, Eric D. Brown, Christopher T. Walsh   +2 more
openalex   +1 more source

Data from Heat Shock Protein 90 Regulates the Metaphase-Anaphase Transition in a Polo-Like Kinase-Dependent Manner

, 2023
Guillermo de Cárcer
openalex   +1 more source

T cells, the next big target in axSpA?

Arthritis &Rheumatology, Accepted Article.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells.
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source