Heat stress-induced heat shock protein 90 alpha family class A member 1 upregulation stabilizes yes-associated protein through ubiquitination inhibition to boost hepatic cancer radiofrequency hyperthermia resistance. [PDF]
Bao Z, Jiang Y, Liang W, Zhang D, Guo L.
europepmc +1 more source
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Advanced Glycation End-Product-Modified Heat Shock Protein 90 May Be Associated with Urinary Stones. [PDF]
Takata T +6 more
europepmc +1 more source
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu +12 more
wiley +1 more source
Construction of a CO2‐Fixing Compartment Using a Shape‐Transforming DNA Scaffold
A shape‐transforming DNA scaffold encapsulates RuBisCO within a controllable, self‐contacting compartment that mimics the carboxysome. The scaffold switches between open and closed states, enabling direct comparison of identical enzyme populations in different microenvironments.
Hui Yang +6 more
wiley +1 more source
Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. [PDF]
Huang L +9 more
europepmc +1 more source
Harnessing Acoustic Cavitation Energy for the Selective Degradation of Impurities in Glucose Syrup
The energy released during the implosion of acoustic cavitation bubbles can be harnessed and selectively transferred to a target solute, enabling its specific decomposition without degrading other solutes present in the solution. This proof of concept was demonstrated in the degradation of impurities present in trace amount in glucose syrup.
Shambel Getachew Wasse +2 more
wiley +1 more source

