Results 221 to 230 of about 3,554,762 (254)

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Heat shock proteins related signature characterizes immune status and predicts prognosis of gliomas. [PDF]

Sci Rep
Sun Z, Wan H, Du M, Guo Y, Tao R, Zhao X, Zhang Y, Yang P, Zhou D.   +8 more
europepmc   +1 more source

Machine Learning Interatomic Potentials for Energy Materials: Architectures, Training Strategies, and Applications

Advanced Energy Materials, EarlyView.
Machine learning interatomic potentials bridge quantum accuracy and computational efficiency for materials discovery. Architectures from Gaussian process regression to equivariant graph neural networks, training strategies including active learning and foundation models, and applications in solid‐state electrolytes, batteries, electrocatalysts ...
In Kee Park, Saeed Pourasad, Jinhong Mun, Arunkumar Chitteth Rajan, Tae Hyeon Park, Anand Rohit, Mohammad Zafari, Tan‐Lien Pham, Eunjae Jung, Bonseung Koo, Miran Ha, Gi Beom Sim, Hyun Gyu Park, Won Woong Choi, Kwanghyeon Jo, Soohaeng Yoo Willow, David ChangMo Yang, Chang Woo Myung, Geunsik Lee, Kwang S. Kim   +19 more
wiley   +1 more source

Exploring the Role of Heat Shock Proteins in Neuroimmune Modulation in Rheumatoid Arthritis: Insights from a Rat Model. [PDF]

Int J Mol Sci
Fouani M, Scalia F, Mangano GD, Rappa F, Abou-Kheir W, Leone A, Lawand N, Barone R.   +7 more
europepmc   +1 more source

Effects of Outsourced Agricultural Extension Services on the Technical Efficiency and Financial Returns of Soybean Farms in Northern Cameroon

Agribusiness, EarlyView.
ABSTRACT In the agricultural landscape of most developing countries, the last decade has witnessed the expansion of outsourced agricultural extension services. Private firms and nongovernmental organizations focused on delivering agricultural extension and advisory services to farmers have emerged.
Boris D. Soh Wenda, Doria A. Medondjeu, Dorothy E. Fon, Stefan Sieber   +3 more
wiley   +1 more source

A Study on the Temperature-Dependent Behavior of Small Heat Shock Proteins from Methanogens. [PDF]

Int J Mol Sci
Kurokawa N, Ogawa M, Midorikawa R, Kanno A, Naka W, Noguchi K, Morishima K, Inoue R, Sugiyama M, Yohda M.   +9 more
europepmc   +1 more source

Food Security Strategy, Macroeconomic Dynamics and Food Import Sensitivity in Qatar

Agribusiness, EarlyView.
ABSTRACT Qatar has limited agricultural land and water resources and therefore remains highly dependent on food imports. This structural dependency makes Qatar vulnerable to external shocks such as the recent Gulf crisis, threatening food security and disrupting global supply chains. In response to previous shocks, Qatar started implementing a National
Hansini Ranjan, Simeon Kaitibie, Alanoud Ali S. Al‐Maadid, John N. Ng'ombe, Ishrat Hossain, Mostafizur Rahman   +5 more
wiley   +1 more source

Modulation of Heat Shock Proteins Levels in Health and Disease: An Integrated Perspective in Diagnostics and Therapy. [PDF]

Cells
Mikhailova E, Sokolenko A, Combs SE, Shevtsov M.   +3 more
europepmc   +1 more source

Implication of Two Small Heat Shock Proteins in the Thermotolerance of <i>Bradysia odoriphaga</i> (Diptera: Sciaridae) Yang et Zhang. [PDF]

Insects
Cheng J, Zheng H, Feng S, Cao W, Wu Q, Song J.   +5 more
europepmc   +1 more source

The Role of <i>Helicobacter pylori</i> Heat Shock Proteins in Gastric Diseases' Pathogenesis. [PDF]

Int J Mol Sci
Manna OM, Caruso Bavisotto C, Gratie MI, Damiani P, Tomasello G, Cappello F.   +5 more
europepmc   +1 more source