Results 201 to 210 of about 569,417 (300)

The heat shock response in plants: new insights into modes of perception, signaling, and the contribution of hormones. [PDF]

J Exp Bot
Dündar G, Ramirez VE, Poppenberger B.
europepmc   +1 more source

Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1-mediated heat shock response. [PDF]

PLoS Biol, 2023
Miles J, Townend S, Milonaitytė D, Smith W, Hodge F, Westhead DR, van Oosten-Hawle P.   +6 more
europepmc   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Response and adaptation of the transcriptional heat shock response to pressure. [PDF]

Front Microbiol
Coffin CH, Fisher LA, Crippen S, Demers P, Bartlett DH, Royer CA.   +5 more
europepmc   +1 more source

Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response. [PDF]

Pharm Biol, 2022
Shen Q, Chen Q, Liu Y, Xue X, Shen X, He Q, Wang G, Han F.   +7 more
europepmc   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source

Dissecting the impact of heat stress on heat-shock response and skin microbiota in farmed fish in a recirculating aquaculture system in Singapore. [PDF]

Microbiol Spectr
Ng TH, M S, Chew XZ, Nair T, Chow JW, Low A, Seedorf H, Bastos Gomes G.   +7 more
europepmc   +1 more source

Human herpesvirus 6A nuclear matrix protein U37 interacts with heat shock transcription factor 1 and activates the heat shock response. [PDF]

J Virol, 2023
Huang JR, Arii J, Hirai M, Nishimura M, Mori Y.   +4 more
europepmc   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Resveratrol protects male <i>Drosophila melanogaster</i> from heat stress-induced paralysis through a mechanism independent of heat shock response activation. [PDF]

MicroPubl Biol
Webb N, Bricker R, Skalos T, Choi A, Shirk A, Hrizo SL, Buckley MS.   +6 more
europepmc   +1 more source