Results 31 to 40 of about 2,047,625 (245)

The burden of heat-related stroke mortality under climate change scenarios in 22 East Asian cities

Environment International, 2022
Background: Stroke is a leading cause of death and disability in East Asia. Owing to the aging population and high prevalence of stroke, East Asia might suffer a disproportionately heavy burden of stroke under the changing climate.
Lu Zhou, Cheng He, Ho Kim, Yasushi Honda, Whanhee Lee, Masahiro Hashizume, Renjie Chen, Haidong Kan   +7 more
doaj   +1 more source

Factors associated with cardiovascular diseases according to Cox regression in patients with heat stroke, other heat-related illnesses and Non-heat-ielated illnesses.

, 2019
Factors associated with cardiovascular diseases according to Cox regression in patients with heat stroke, other heat-related illnesses and Non-heat-ielated illnesses.
Chi-Hsiang Chung (306301), Shih-Hung Tsai (314176), Jen-Chun Wang (6330968), Wu-Chien Chien (306300), Chih-Yuan Lin (484480), Pauling Chu (127132)   +5 more
core   +1 more source

The Virtual International Stroke Trials Archive [PDF]

, 2007
Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal.
Donnan, Geoffrey A., Kaste, M., HENNERICI, Michael G, Teal, P., Gregson, B.A., Hacke, Werner, Marler, J.R., Marler, John R., Fisher, M., GREGSON, Barbara A, Wahlgren, Nils-Gunnar, Curram, John, Grotta, J., MARLER, John R, Davis, Stephen M., Sacco, Ralph L., Donnan, G.A., Myzoon, Ali, Bath, Philip M.W., Teal, Philip, WEIR, Christopher J, Weir, C.J., Gregson, Barbara A., Fisher, Marc, Hommel, Marc, Hacke, W., BATH, Philip M. W, Sacco, R.L., Diener, Hans-Christoph, Warach, S., DONNAN, Geoffrey A, Hennerici, Michael G., Wahlgren, N.-G., Lees, K.R., Grotta, James, Hennerici, M.G., Kaste, Markku, Weir, Christopher J., Warach, Steven, Lees, Kennedy R., DAVIS, Stephen M, Bath, P.M.W., Ali, M., Curram, J., Diener, H.-C., Davis, S.M., SACCO, Ralph L, Hommel, M., LEES, Kennedy R, Ali, Myzoon; id_orcid, ALI, Myzoon   +50 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability [PDF]

Endovascular therapy; Ischemic stroke; ReperfusionTerapia endovascular; Ictus isquémico; ReperfusiónTeràpia endovascular; Ictus isquèmic; ReperfusióBackground and Purpose We compared the outcomes of endovascular therapy (EVT) in an extended time window ...
Uchida, Kazutaka, Yamagami, Hiroshi, Siegler, James, Nogueira, Raul, Tanaka, Kanta, Requena, Manuel, Ribo, Marc, Olive-Gadea, Marta, Qureshi, Muhammad M.   +8 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Epidemiological characteristics of heat stroke and association between heatwave and heat stroke in Jinan City, 2017—2022

环境与职业医学
BackgroundIn recent years, regional high-temperature weather in summer occurs frequently in China. Heat stroke is the most representative meteorological disease caused by high temperature.
Huiyun CHANG, Bing SHAN, Xiumiao PENG, Tiantian LI, Liangliang CUI   +4 more
doaj   +1 more source

Drug-Induced Heat Stroke

, 1978
It is seldom recognized that heat stroke can be precipitated by drug therapy. Drugs that alter normal body thermoregulation and the mechanisms of drug action on thermoregulation are discussed, together with normal body thermoregulation and heat stroke ...
Jay M. Mirtallo
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

PLCd4 signaling-mediated PI4P synthesis drives macrophage NLRP3 inflammasome activation to promote heat stroke-induced tissue injury

Cell Reports
Summary: Heat stroke causes life-threatening systemic inflammation and multiorgan injury, but the intracellular mechanisms that sustain inflammatory amplification after heat exposure remain unclear.
Riqing Wei, Wenqian Zheng, Chenxin Liu, Dinghao Dang, Xinyu Deng, Xiaoting Hu, Hui Liang, Xi Luo, Jiayi Tang, Wei Zhu, Shuogui Xu, Ru Li, Qiang Ma   +12 more
doaj   +1 more source