Results 61 to 70 of about 222,334 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hardware and Software Implementation for Solar Hot Water System in Northern Regions of Russia

Energies, 2022
Acceleration of energy transition will become the crucial social, political and technical challenge of the 21st century and will be largely associated with the growing use of renewable energy sources, including solar power.
Nikolay Tsvetkov, Stanislav Boldyryev, Aleksandr Shilin, Yuriy Krivoshein, Aleksandr Tolstykh   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analysis of the Operation Characteristics of a Hybrid Heat Pump in an Existing Multifamily House Based on Field Test Data and Simulation

Energies, 2022
Unrenovated multifamily houses in Germany are mostly heated by fossil heat generators; therefore, measures are required for CO2 emission reduction. The use of air–water heat pumps is restricted by high required flow temperatures and heat output but can ...
Daniel Neubert, Christian Glück, Julian Schnitzius, Armin Marko, Jeannette Wapler, Constanze Bongs, Clemens Felsmann   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Increasing the Efficiency of Ecological Solar Panels Combined with the Building’s Roof

Applied Sciences
This article is devoted to increasing the efficiency of ecological solar panels with their combination with the house’s roof. A solar panel construction that combines both the solar collector and the building cover is considered.
Orest Voznyak, Mariana Kasynets, Stepan Shapoval, Olena Savchenko, Iryna Sukholova, Nadiia Spodyniuk, Oleksandr Dovbush   +6 more
doaj   +1 more source

Aerodynamic processes and heat exchange in the furnace of a steam boiler with a secondary emitter

Alexandria Engineering Journal, 2019
The use of water-tube boilers is common in industrial and municipal boiler houses and they are used as the sources of heat and steam supply. The introduction of measures that ensure environmental performance at an acceptable level, the use of modern ...
Andriy Redko, Rafael Dzhyoiev, Anastasiya Davidenko, Anna Pavlovskaya, Serhii Pavlovskiy, Igor Redko, Nataliia Kulikova, Oleksandr Redko   +7 more
doaj   +1 more source

Modelling and Simulation of Underfloor Heating System Supplied from Heat Pump [PDF]

2016 UKSim-AMSS 18th International Conference on Computer Modelling and Simulation (UKSim), 2016
© 2016 IEEE. This paper describes thermal capacity and thermal inertia of an underfloor heating system supplied from a heat pump. A MATLAB/SIMULINK based thermal model of the system have been developed and presented with detailed mathematical equations.
Muhammad Akmal, Brendan Fox
openaire   +1 more source