Results 81 to 90 of about 1,201,680 (348)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Similarities and differences between flow boiling in microchannels and pool boiling [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +1 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Numerical evaluation of heat transfer enhancement due to annular electroconvection induced by injection in a dielectric liquid [PDF]
, 2016 Two-dimensional numerical simulations are carried out to evaluate the enhancement of natural convection heat transfer in a dielectric liquid resulting from injection induced annular electro-convection.
Louste, Christophe +4 more
core +3 more sources
Enhanced Condensation Heat Transfer
JSME International Journal Series B, 2006 The paper gives some personal observations on various aspects of enhanced condensation heat transfer. The topics discussed are external condensation (horizontal low-finned tubes and wire-wrapped tubes), internal condensation (microfin tubes and microchannels) and Marangoni condensation of binary mixtures.
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Advances in Mechanical Engineering, 2014 Modern gas turbine blade is operating at high temperature which requires abundant cooling. Considering both heat transfer rate and pumping power for internal passages, developing efficient cooling passages is of great importance.
Di Zhang +3 more
doaj +1 more source
Experimental investigation of heat transfer in a tube heat exchanger with airfoil-shaped insert
Case Studies in Thermal Engineering, 2019 In this present study, the novel insert for heat exchanger is presented. The airfoil-shaped insert, Modified NACA0024, is chosen to improve the heat transfer performance in the tube.
Suabsakul Gururatana, Sompol Skullong
doaj +1 more source
Natural convection in high temperature flat plate latent heat thermal energy storage systems [PDF]
, 2016 The impact of natural convection on melting in high temperature flat plate latent heat thermal energy storage systems is studied with an experimentally validated numerical model in a parameter study with various widths and heights of enclosure dimensions.
Felbinger, Jonina +2 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source