Results 91 to 100 of about 929,788 (310)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Performance Enhancement of Convective Heat Transfer in Double Pipe Heat Exchangers using Different Vortex Generators’ Configurations [PDF]

E3S Web of Conferences
Double-pipe heat exchangers (DPHEs) are important devices used for efficient heat transfer between fluids, affecting system energy Performance. This study explores different configurations for the integration of vortex generators (VGs) into DPHEs to ...
El Hassan Mouhammad, Al Rajeh Abdullah Y., Bukharin Nikolay, AlGhannam Yara, Albakawi Jawaher   +4 more
doaj   +1 more source

Simulating the Performance of a Heat Exchanger During Frosting [PDF]

, 2001
Factors affecting frost distribution are explored using a finite element model, developed and validated using a full-scale 8-row heat exchanger in a wind tunnel.
Bullard, C.W., Hrnjak, P.S., Verma, P.
core  

Improved prediction of shell side heat transfer in horizontal evaporative shell and tube heat exchangers [PDF]

, 2008
This paper presents an improved prediction method for the heat transfer and pressure drop in the shell side of a horizontal shell and tube evaporator. The results from an experimental test program are used in which a wide range of evaporating two-phase ...
Dempster, W.M., Doo, G.H., DTI (Funder), EPSRC (Funder), Hyprotech UK Ltd (now Aspen Technology Inc.) (Funder), McNaught, J.M., TUVNEL (Funder)   +6 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Relationship between chevron angle and heat transfer performance of plate heat exchangers

Case Studies in Thermal Engineering
The chevron angle (β) of a plate heat exchanger significantly affects its heat transfer performance. This study aims to quantify the relation between heat transfer performance and chevron angle.
Xiaowei Zhu
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Survey of aircraft electrical power systems [PDF]

, 1972
Areas investigated include: (1) load analysis; (2) power distribution, conversion techniques and generation; (3) design criteria and performance capabilities of hydraulic and pneumatic systems; (4) system control and protection methods; (5) component and
Brandner, J. J., Lee, C. H.
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Sintered Wick Heat Pipes with Excellent Heat Transfer Capabilities—Case Study

Energies
A sintered wick was formed in a heat pipe through the process of sintering a mixture of copper powder with particle sizes of 100 µm and 200 µm, mixed with a pore-forming agent.
Im-Nam Jang, Yong-Sik Ahn
doaj   +1 more source