Results 91 to 100 of about 1,323,075 (288)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Universal Heat Transport in Sr2RuO4

open access: yesPhysical review letters, 2002
We present the temperature dependence of the thermal conductivity kappa(T) of the unconventional superconductor Sr_2RuO_4 down to low temperatures (100 mK). In T -> 0 K limit we found a finite residual term in kappa/T, providing clear evidence for the superconducting state with an unconventional pairing.
Suzuki, M   +5 more
openaire   +3 more sources

Effects of polymer additives in the bulk of turbulent thermal convection

open access: yes, 2015
We present experimental evidence that a minute amount of polymer additives can significantly enhance heat transport in the bulk region of turbulent thermal convection. The effects of polymer additives are found to be the \textit{suppression} of turbulent
Funfschilling, Denis   +5 more
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Radiant heat source, vacuum bag, provide portable bonding oven [PDF]

open access: yes, 1967
Portable bonding oven is formed to any desired size or configuration to attach doublers and brackets to the surfaces of large structures. A radiant heat source is used in combination with a heat resistant transport vacuum bag and a black heat absorbing ...
Nicholls, A. H.
core   +1 more source

From thermal rectifiers to thermoelectric devices

open access: yes, 2015
We discuss thermal rectification and thermoelectric energy conversion from the perspective of nonequilibrium statistical mechanics and dynamical systems theory. After preliminary considerations on the dynamical foundations of the phenomenological Fourier
A. Dhar   +142 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

A fundamental study on the heat transport characteristics in a pulsating heat pipe by using a forced oscillation system (Measurement of effective thermal conductivity)

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Recently, highly efficient small heat transport devices have been required. In particular, pulsating heat pipes (PHP) have come to draw a lot of attention. The contribution of sensible heat transport and latent heat transport in oscillating working fluid,
Masayoshi MIURA   +2 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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