Results 71 to 80 of about 418,548 (318)

Entropy Generation Analysis and Thermodynamic Optimization of Jet Impingement Cooling Using Large Eddy Simulation

Entropy, 2019
In this work, entropy generation analysis is applied to characterize and optimize a turbulent impinging jet on a heated solid surface. In particular, the influence of plate inclinations and Reynolds numbers on the turbulent heat and fluid flow properties
Florian Ries, Yongxiang Li, Kaushal Nishad, Johannes Janicka, Amsini Sadiki   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Heat and Mass Transfer during Baking: Product Quality aspects [PDF]

, 2005
Most food product qualities are developed during heating processes. Therefore the internal heating and mass transfer of water are important aspects in food processing. Heating of food products is mostly induced by convection heating.
Hadiyanto, H., hadiyanto, hady
core  

Modeling of Mechanical Interaction of Reinforcement with Matrix Composite

Механика машин, механизмов и материалов, 2009
There is solved the problem on determination influence of contact parameters between composite reinforcement and a matrix on strengthening and stiffness of a supporting structure. It is executed on a finite element modelling basis.
Yu.M. Pleskachevsky , A.O. Shimanovsky , O.I. Yakubovich , G.M. Kuziomkina   +3 more
doaj  

Modeling the Operating Conditions of Electric Power Systems Feeding DC and AC Traction Substations

Energies
This paper presents the findings of the research aimed at developing computer models to determine the operating conditions in electric power systems (EPSs) feeding DC and AC railway substations.
Iliya K. Iliev, Andrey V. Kryukov, Konstantin V. Suslov, Aleksandr V. Cherepanov, Nguyen Quoc Hieu, Ivan H. Beloev, Yuliya S. Valeeva   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dynamics of Circular Metal-Polymeric Plates on an Elastic Foundation. Part I. FREE VIBRATIONS

Механика машин, механизмов и материалов, 2008
The axisymmetrical free vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation are explored. Reaction of foundation was described on the base of Winkler’s model.
Yu.M. Pleskatshevsky, E.I. Starovoitov , D.V. Leonenko   +2 more
doaj  

Modeling of Electromagnetic Fields of the Traction Network Taking into Account the Influence of Metal Structures

Applied Sciences
The paper addresses the issues of electromagnetic safety in traction networks of 25 kV AC railways. The purpose of the research is to develop digital models to determine the strengths of electromagnetic fields (EMFs) created by traction networks near ...
Iliya Iliev, Andrey Kryukov, Konstantin Suslov, Ekaterina Voronina, Andrey Batukhtin, Ivan Beloev, Yuliya Valeeva   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A way to visualise heat transfer in 3D unsteady flows

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Speetjens, MFM   +1 more
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