Results 51 to 60 of about 418,548 (318)

Local Heat Transfer Distribution and Effect of Instabilities During Flow Boiling in a Silicon Microchannel Heat Sink

open access: yes, 2011
Flow boiling of the perfluorinated dielectric fluid FC-77 in a silicon microchannel heat sink is investigated. The heat sink contains 60 parallel microchannels each of 100 lm width and 389 lm depth.
Garimella, Suresh V.   +4 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Investigation of heat transfer in metal-foam tubes [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Nowadays metallic foams attract increasing attention in making compact heat exchangers due to its advanced thermal properties.
Lu, Wei
core  

Vibrations of Circular Metal-Polymeric Plates on an Elastic Foundation. Part II. Forced Vibrations

open access: yesМеханика машин, механизмов и материалов, 2009
The axisymmetrical forced vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation are explored under action of divided local loadings: rectangular, sinusoidal, parabolic.
Yu.M. Pleskachevsky   +2 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Fundamentals of Climatology for Engineers: Lecture Note

open access: yesEng, 2022
The study of climatology serves as a foundation for students who wish to specialize in water resources, hydrology, or environmental engineering. Climatology is the study of long-term average weather patterns.
Shiblu Sarker
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Temperature influence on internal reforming and methane direct oxidation in solid oxide fuel cells [PDF]

open access: yesНанотехнологии в строительстве, 2018
Nanotechnology is currently the main mega-project in science in general and particularly in energy. According to experts of the modern scientific world, it is possible to solve global energy problems only with the help of a convergent NBIC-technology ...
BAIKOV Igor Ravilevich   +3 more
doaj   +1 more source

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