Results 61 to 70 of about 4,092,332 (300)
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Numerical Simulation of Heat Transport from the Electric Arc Furnace to the Heat Recovery System
, 2016 The paper presents a numerical model of heat transport from melting charge of the electric arc furnace designed for ferroalloy production, into a cooled roof of the electric arc furnace from which waste heat is led to the heating system of a company. The
Stanislav Gavlas +4 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The Bending of Three-Layer Elastic Core with Variable Stiff Shell
Механика машин, механизмов и материалов, 2008 The bending of three-layer elastic core with variable thickness of one of two stiff shells is considered. To describe kinematics of asymmetrical over thickness pack of the core the hypotheses of the broken normal are accepted.
Yu.M. Pleskachevsky, E.E. Starovoytova
doaj
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Airborne lidar observations of water vapour variability and transport [PDF]
, 2012 Water vapour, a minor constituent of the earth’s atmosphere, plays a major role in the radiation budget and the water cycle with important implications for weather and climate. Due to the heterogeneous distribution of its sources, evaporation, and sinks,
Fischer, Lucas +4 more
core
Dynamic heat transport in open quantum systems [PDF]
Heat transport in driven nanoscale systems plays a critical role in quantum technologies and in non-equilibrium thermodynamics. More specifically, the investigation of time-dependent temperatures in quantum systems is a developing field that has seen ...
de Castro Portugal, Pedro Vinicius
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Vibration of Circular Metal-Polymeric Plates on an Elastic Foundation under Heat Stroke
Механика машин, механизмов и материалов, 2009 The axisymmetrical vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation ander heat stroke are explored. For the kinematics description asymmetrical on the thickness of package accepted hypothesises broken normal ...
Yu.M. Pleskachevsky +3 more
doaj