Results 81 to 90 of about 4,092,332 (300)
Entropy, 2019 In this work, entropy generation analysis is applied to characterize and optimize a turbulent impinging jet on a heated solid surface. In particular, the influence of plate inclinations and Reynolds numbers on the turbulent heat and fluid flow properties
Florian Ries +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Applied SciencesThe paper addresses the issues of electromagnetic safety in traction networks of 25 kV AC railways. The purpose of the research is to develop digital models to determine the strengths of electromagnetic fields (EMFs) created by traction networks near ...
Iliya Iliev +6 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Influence of Engine Load on Soot Mass Concentration and Morphology in Diesel Exhaust
AtmosphereThis study investigates the relationship between exhaust gas composition, particle number (PN) emissions, and soot microstructure of a 1.9 L compression-ignition engine operated under six controlled steady-state load regimes at 2000 min−1.
Iliyan Damyanov +3 more
doaj +1 more source
The fractional heat equation [PDF]
, 2012 Paper presented at the 9th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Malta, 16-18 July, 2012.This paper extends the method, in which a Volterra-type integral equation that relates the local values of temperature and
Poletkin, KV +3 more
core
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Investigation Perspectives of Dynamics of Tank Vehicles for Liquid Loads
Механика машин, механизмов и материалов, 2007 It is analysed a current state and investigation perspectives of dynamics truck and rail tank vehicles. There are resulted equations presenting movement of considered system members.
A.O. Shimanovsky +2 more
doaj
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source