Results 81 to 90 of about 871,068 (305)
Microstructural changes caused by thermal treatment and their effects on mechanical properties of a gamma/gamma prime - delta eutectic alloy [PDF]
Microstructural changes due to thermal treatments of a directionally solidified gamma/gamma'-delta eutectic alloy were investigated. Aging treatments of 8 to 48 hours and ranging from 750 to 1120 C were given to the alloy in both its as directionally ...
Dreshfield, R. L., Tewari, S. N.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Magnetochemistry, 2019 First-order phase transitions (FOPT) and second-order phase transitions (SOPT) are commonly observed in Cu alloys containing lanthanide elements, due to their electronic configuration, and have an important effect on the optimization of their ...
E. J. Gutiérrez Castañeda +7 more
doaj +1 more source
Treatments of flows through micro-channels based on the Extended Navier-Stokes-Equations [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011) +5 more
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Creep behaviour of as received, aged and cold worked INCONEL 617 at 850 °C and 950 °C [PDF]
, 2010 The effect of initial microstructure on alloy 617 creep behaviour has been investigated at 850 °C and 950 °C. The solution treated material shows non-classical creep behaviour at both temperatures with a strain rate drop at the beginning of the tests ...
Chomette, Sébastien +2 more
core +3 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
High temperature annealing of micrometric Zn2SiO4:Mn phosphor powders in fluidized bed [PDF]
, 2008 Micrometric Zn1.8Mn0.2SiO4 phosphor powders prepared by spray pyrolysis have been annealed between 900 and 1200°C under ambient air atmosphere to exalt their luminescence properties. Two original gas-solid fluidization processes have been tested in order
Alavi, Shila +2 more
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Post weld heat treatment effects on SMSS deposit mechanical properties [PDF]
, 2015 Supermartensitic stainless steels have been developed as an alternative technology, mainly for oil and gas industries. In these steels, the post-weld heat treatments are usually double tempering treatments, to ensure the complete tempering of martensite ...
Zappa, Sebastián +3 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source