Results 271 to 280 of about 4,735,245 (382)

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

Advanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret, Jean‐Baptiste Billeau, Michael H. Weber, Derek H. Rosenzweig, Stephan Reuter   +4 more
wiley   +1 more source

Utility of binding protein fusions to immunoglobulin heavy chain constant regions from mammalian and avian species. [PDF]

J Biol Chem
Zhu N, Smallwood PM, Williams J, Wang Y, Nathans JH.   +4 more
europepmc   +1 more source

Variable Region Sequences of Five Human Immunoglobulin Heavy Chains of the V _H III Subgroup: Definitive Identification of Four Heavy Chain Hypervariable Regions

, 1974
J. Donald Capra, J. Michael Kehoe
openalex   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Smooth Muscle Myosin Heavy Chain Expression in Nodal and Extranodal Follicular Dendritic Cell Sarcoma. [PDF]

Appl Immunohistochem Mol Morphol
Kelley JT, Amoth HM, Lopez-Hisijos N, Hrycaj S, Valdez R, Rottmann D.   +5 more
europepmc   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2. [PDF]

Hum Genomics
Malaspina P, Jodice C, Ciminelli BM, Biancolella M, Colona VL, Latini A, Leonardis F, Rogliani P, Novelli A, Novelli G, Novelletto A.   +10 more
europepmc   +1 more source

Size differences among immunoglobulin heavy chains from phosphorylcholine-binding proteins.

, 1976
Stuart Rudikoff, Michael Potter
openalex   +1 more source

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Author Correction: The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2. [PDF]

Sci Rep
Maimaiti M, Sakamoto S, Sugiura M, Kanesaka M, Fujimoto A, Matsusaka K, Xu M, Ando K, Saito S, Wakai K, Imamura Y, Nakayama K, Kanai Y, Kaneda A, Ikehara Y, Ikeda JI, Anzai N, Ichikawa T.   +17 more
europepmc   +1 more source