Results 291 to 300 of about 4,061,678 (356)
Some of the next articles are maybe not open access.
Current Treatment Options in Oncology, 2002
The heavy chain diseases (HCDs) are rare B-cell malignancies that are distinguished by the production of a monoclonal immunoglobulin heavy chain (HC) without an associated light chain by the malignant B-cells. There are three types of HCD defined by the class of immunoglobulin (Ig) HC produced: IgA (alpha-HCD), IgG (gamma-HCD), and IgM (mu-HCD).
Thomas E, Witzig +1 more
openaire +2 more sources
The heavy chain diseases (HCDs) are rare B-cell malignancies that are distinguished by the production of a monoclonal immunoglobulin heavy chain (HC) without an associated light chain by the malignant B-cells. There are three types of HCD defined by the class of immunoglobulin (Ig) HC produced: IgA (alpha-HCD), IgG (gamma-HCD), and IgM (mu-HCD).
Thomas E, Witzig +1 more
openaire +2 more sources
Clinics in Laboratory Medicine, 1986
A review of alpha-heavy chain disease (AHCD) emphasizing its histopathology and associated lesions is presented. Unusual clinicopathologic presentations and modern concepts regarding histogenesis of AHCD in the light of recent immunohistochemical findings are discussed.
P, Haghighi, P L, Wolf
openaire +2 more sources
A review of alpha-heavy chain disease (AHCD) emphasizing its histopathology and associated lesions is presented. Unusual clinicopathologic presentations and modern concepts regarding histogenesis of AHCD in the light of recent immunohistochemical findings are discussed.
P, Haghighi, P L, Wolf
openaire +2 more sources
A Review on Heavy Metals Contamination in Soil: Effects, Sources, and Remediation Techniques
Soil & sediment contamination, 2019Soil heavy metal pollution has become a worldwide environmental issue that has attracted considerable public attention, largely from the increasing concern for the security of agricultural products.
Changfeng Li +6 more
semanticscholar +1 more source
Archives of Internal Medicine, 1972
To the Editor. —We read with interest the paper in the September issue1 on αheavy chain disease in which the pathological immunoglobulin disappeared with chemotherapy. The authors state that up to the time of acceptance of their paper all cases of so-called Mediterranean lymphoma and α-chain disease have occurred either in Arabs or oriental Jews in ...
B H, Novis, S, Bank
openaire +3 more sources
To the Editor. —We read with interest the paper in the September issue1 on αheavy chain disease in which the pathological immunoglobulin disappeared with chemotherapy. The authors state that up to the time of acceptance of their paper all cases of so-called Mediterranean lymphoma and α-chain disease have occurred either in Arabs or oriental Jews in ...
B H, Novis, S, Bank
openaire +3 more sources
Structure of Abnormal Heavy Chains in Human Heavy-chain-deposition Disease
European Journal of Biochemistry, 1995The sequences of two immunoglobulin gamma 1 heavy chains involved in the formation of non-amyloid tissue deposits were determined in two patients (RIC and THR) affected with plasma cell monoclonal proliferation and heavy-chain-deposition disease. The proliferating plasma cells of patients RIC and THR synthesized truncated gamma 1 chains of 45 kDa and ...
A A, Khamlichi +3 more
openaire +2 more sources
1986
Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
openaire +5 more sources
Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
openaire +5 more sources
European Journal of Immunology, 1978
AbstractUsing cultured mouse myeloma cells, it has been possible to derive cells which are now synthesizing products similar to human heavy chain disease proteins. An initial mutant was isolated which synthesized a heavy chain with an internal deletion and a normal light chain.
openaire +2 more sources
AbstractUsing cultured mouse myeloma cells, it has been possible to derive cells which are now synthesizing products similar to human heavy chain disease proteins. An initial mutant was isolated which synthesized a heavy chain with an internal deletion and a normal light chain.
openaire +2 more sources
1994
Abstract The rat clathrin heavy chain is encoded by one gene, and there is no evidence for the existence of pseudogenes. Since the same single mRNA species is present in various tissues, it is believed that within the resolution of the RNA blots, clathrin heavy chain is not alternatively spliced.
openaire +1 more source
Abstract The rat clathrin heavy chain is encoded by one gene, and there is no evidence for the existence of pseudogenes. Since the same single mRNA species is present in various tissues, it is believed that within the resolution of the RNA blots, clathrin heavy chain is not alternatively spliced.
openaire +1 more source
Nihon rinsho. Japanese journal of clinical medicine, 1995
Heavy chain diseases (HCDs) are monoclonal, lymphoproliferative disorders characterized by the production of incomplete heavy chains, devoid of light chains. Since the first report of gamma-HCD in 1964, alpha-HCD and mu-HCD have also been described. The clinical features of gamma-HCD may vary considerably.
S, Nomura, T, Kanoh
openaire +1 more source
Heavy chain diseases (HCDs) are monoclonal, lymphoproliferative disorders characterized by the production of incomplete heavy chains, devoid of light chains. Since the first report of gamma-HCD in 1964, alpha-HCD and mu-HCD have also been described. The clinical features of gamma-HCD may vary considerably.
S, Nomura, T, Kanoh
openaire +1 more source