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Gastric Alpha Heavy Chain Disease
Oncology, 1987Clinicopathological and immunohistological features of 4 cases of gastric lymphomas with alpha-heavy chain disease (AHCD) are described. Clinically there were no reliable features that could distinguish them from the 'western' types of gastric lymphomas (WGL).
Y.T. Omar, M.F. Tungekar, K. Behbehani
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Diagnosis of Gamma Heavy-Chain Disease
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1981The diagnosis of gamma heavy-chain disease can be made only by immunochemical analysis of serum and urine. The case reported here demonstrates the importance of diligent observation of routine electrophoretic patterns, followed by immunoelectrophoresis where indicated for the identification of abnormal bands.
K R Hine +3 more
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The evolution of alpha heavy chain disease
The American Journal of Medicine, 1976Two patients with alpha heavy chain disease are described. In the first patient, treatment with cyclophosphamide, prednisone and doxycycline was associated with a 28 month-long remission and the disappearance of the paraprotein and lymphoplasmocytic infiltration of the intestine.
Martínez-Vázquez Jm +6 more
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Heavy chain disease: our experience
Clinical Chemistry and Laboratory Medicine (CCLM), 2017Heavy chain disease (HCD) is a rare lymphoproliferative disorder of plasma cells, described for the first time in 1964 by Franklin [1], characterized by production of incomplete monoclonal immunoglobulin heavy chains without associated light chains [2].
Gulli, Francesca +5 more
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Heavy functions for light chains
Nature Medicine, 2002Immunologists are just beginning to understand the early signals required to recruit memory T cells to sites of antigen-specific inflammation. Now it seems that activation of κ light chain–sensitized mast cells by antigen-specific recognition initiates local immune responses (pages 694–701).
Martin Röcken, Lothar Hültner
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Gamma Heavy Chain Disease. Where the Heavy Chains Arise
American Journal of Clinical Pathology, 1983William T. Pastuszak +3 more
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1998
The basic building block of the contractile apparatus in skeletal and cardiac muscle cell is the sarcomere. This multisubunit structure is composed of a precise geometric arrangement of thick filaments sur-rounded by a hexagonal array of thin filaments, each containing actin and the tro-ponin-tropomyosin regulatory complex.
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The basic building block of the contractile apparatus in skeletal and cardiac muscle cell is the sarcomere. This multisubunit structure is composed of a precise geometric arrangement of thick filaments sur-rounded by a hexagonal array of thin filaments, each containing actin and the tro-ponin-tropomyosin regulatory complex.
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New roads and challenges for fuel cells in heavy-duty transportation
Nature Energy, 2021David A Cullen +2 more
exaly
The assembly, regulation and function of the mitochondrial respiratory chain
Nature Reviews Molecular Cell Biology, 2021Irene Vercellino, Leonid A Sazanov
exaly