Results 31 to 40 of about 398,844 (320)

Clathrin heavy chain, light chain interactions. [PDF]

open access: yesThe EMBO Journal, 1983
Purified pig brain clathrin can be reversibly dissociated and separated into heavy chain trimers and light chains in the presence of non-denaturing concentrations of the chaotrope thiocyanate. The isolated heavy chain trimers reassemble into regular polygonal cage structures in the absence of light chains.
Fritz K. Winkler, K. Stanley
openaire   +3 more sources

Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain

open access: yesBiophysics and Physicobiology, 2023
Ciliary bending movements are powered by motor protein axonemal dyneins. They are largely classified into two groups, inner-arm dynein and outer-arm dynein. Outer-arm dynein, which is important for the elevation of ciliary beat frequency, has three heavy
Toshiki Yagi   +3 more
doaj   +1 more source

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

open access: yesFrontiers in Immunology, 2018
We created a novel transgenic rat that expresses human antibodies comprising a diverse repertoire of heavy chains with a single common rearranged kappa light chain (IgKV3-15-JK1).
Katherine E. Harris   +21 more
doaj   +1 more source

Sudden chain energy transfer events in vibrated granular media [PDF]

open access: yesPhysical Review Letters 106, 088001 (2011), 2011
In a mixture of two species of grains of equal size but different mass, placed in a vertically vibrated shallow box, there is spontaneous segregation. Once the system is at least partly segregated and clusters of the heavy particles have formed, there are sudden peaks of the horizontal kinetic energy of the heavy particles, that is otherwise small ...
arxiv   +1 more source

Antibodies in a Heavy Chain Knock-In Mouse Exhibit Characteristics of Early Heavy Chain Rearrangement [PDF]

open access: yesThe Journal of Immunology, 2009
Abstract Studies in autoantibody transgenic mice have demonstrated receptor editing rearrangements at Ab H and L chain loci. However, the physiologic role of H chain editing (VH replacement and rearrangement on the second allele) has been called into question.
Wenzhao Meng   +4 more
openaire   +2 more sources

AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis

open access: yesBMC Nephrology, 2018
Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe   +6 more
doaj   +1 more source

Pinning Model with Heavy Tailed Disorder [PDF]

open access: yesStochastic Process. Appl., 2016, vol. 126, 542-571, 2014
We study the so-called pinning model, which describes the behavior of a Markov chain interacting with a distinguished state. The interaction depends on an external source of randomness, called disorder, which can attract or repel the Markov chain path. We focus on the case when the disorder is heavy-tailed, with infinite mean, while the return times of
arxiv   +1 more source

Fate of in-medium heavy quarks via a Lindblad equation [PDF]

open access: yesJ. High Energ. Phys. (2017) 2017: 64, 2017
What is the dynamics of heavy quarks and antiquarks in a quark gluon plasma? Can heavy-quark bound states dissociate? Can they (re)combine? These questions are addressed by investigating a Lindblad equation that describes the quantum dynamics of the heavy quarks in a medium.
arxiv   +1 more source

AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes

open access: yesFrontiers in Immunology
IntroductionAnalysis of an individual’s immunoglobulin (IG) gene repertoire requires the use of high-quality germline gene reference sets. When sets only contain alleles supported by strong evidence, AIRR sequencing (AIRR-seq) data analysis is more ...
Andrew M. Collins   +16 more
doaj   +1 more source

Immune subtraction for improved resolution in serum protein immunofixation electrophoresis and antibody isotype determination in a patient with autoantibody

open access: yesPractical Laboratory Medicine, 2021
Heavy chain isotypes of low level monoclonal immunoglobulins are sometimes obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins.
Asad Ullah   +4 more
doaj  

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