Results 31 to 40 of about 1,223,101 (358)

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Ahnert-Hilger, G., Dayanithi, G., Gratzl, Manfred, Lnk, H., Nordmann, J. J., Weller, U.   +5 more
core   +1 more source

Search for large topological gaps in atomic spin chains on proximitized superconducting heavy metal layers [PDF]

Communications Physics 6, 83 (2023), 2023
One-dimensional systems comprising s-wave superconductivity with meticulously tuned magnetism and spin-orbit coupling can realize topologically gapped superconductors hosting Majorana edge modes whose stability is determined by the gap's size. The ongoing quest for larger topological gaps evolved into a material science issue.
arxiv   +1 more source

Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

Frontiers in Immunology, 2018
Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjögren’s syndrome (pSS) patients. In
Annie Visser, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Niek de Vries, Niek de Vries, Fred K. L. Spijkervet, Arjan Vissink, Richard J. Bende, Hendrika Bootsma, Frans G. M. Kroese, Nicolaas A. Bos   +11 more
doaj   +1 more source

Light and heavy chain deposition disease with focal amyloid deposition diagnosed with mass spectrometry: a case report

BMC Nephrology, 2023
Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys.
Yuki Shimamoto, Naoki Takahashi, Nagaaki Katoh, Yuki Matsui, Yusuke Mochizuki, Masanori Ito, Masahide Yazaki, Fuyuki Kametani, Kenji Kasuno, Yoshiki Sekijima, Hironobu Naiki, Masayuki Iwano   +11 more
doaj   +1 more source

Early changes in rat diaphragm biology with mechanical ventilation [PDF]

, 2003
To better characterize the effects of 24-hour mechanical ventilation on diaphragm, the expression of myogenic transcription factors, myosin heavy chains, and sarcoplasmic/endoplasmic reticulum calcium-ATPase pumps was examined in rats.
Cadot, Pascal, De Paepe, Kristel, Decramer, Marc, Gayan-Ramirez, Ghislaine, Rácz, Gábor Z., Testelmans, Dries, Wuytack, Frank, Zádor, Ernő   +7 more
core   +1 more source

Vibration of a Flexible Hanging Chain with a Mass on the End in a Nonstationary Regime of the Motion Mechanism in Hoisting Machines [PDF]

Journal of Applied and Computational Mechanics
The article is focused on the vibrations of a heavy chain with a mass on the end when the hoisting machines are in a nonstationary regime of motion, assuming that motor or brake torque is a linear function of the speed of the motion mechanism.
Vassil Zlatanov, Svetoslav Nikolov
doaj   +1 more source

Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies

Antibodies, 2020
We report the novel crystal structure and characterization of symmetrical, homodimeric humanized heavy-chain-only antibodies or dimers (HC2s). HC2s were found to be significantly coexpressed and secreted along with mAbs from transient CHO HC/LC ...
Carl Mieczkowski, Soheila Bahmanjah, Yao Yu, Jeanne Baker, Gopalan Raghunathan, Daniela Tomazela, Mark Hsieh, Mark McCoy, Corey Strickland, Laurence Fayadat-Dilman   +9 more
doaj   +1 more source

Clathrin heavy chain, light chain interactions. [PDF]

The EMBO Journal, 1983
Purified pig brain clathrin can be reversibly dissociated and separated into heavy chain trimers and light chains in the presence of non-denaturing concentrations of the chaotrope thiocyanate. The isolated heavy chain trimers reassemble into regular polygonal cage structures in the absence of light chains.
Fritz K. Winkler, K. Stanley
openaire   +3 more sources

Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4 [PDF]

, 2004
86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally
Allen RC, Aruffo A, Bonhomme D, Fuleihan R, Lin Q, Mayer L, Ramesh N, Seyama K, Webster ADB, WHO Scientific Group.   +9 more
core   +3 more sources

Noradrenaline release from permeabilized synaptosomes is inhibited by the light chain of tetanus toxin [PDF]

, 1992
Noradrenaline release from rat brain cortical synaptosomes permeabilized with streptolysin O can be triggered by μM concentrations of free Ca2+. This process was inhibited within minutes by tetanus toxin and its isolated light chain, but not by its heavy
Ahnert-Hilger, Ahnert-Hilger, Bittner, Bittner, Bittner, Bradford, Brigitte Stecher, Dayanithi, Dayanithi, De, Dekker, Dekker, Dunkley, Eisel, Föhr, Habermann, Hens, Jacques J.H. Hens, Kistner, Maisey, Manfred Gratzl, Matsuda, McInnes, Mochida, Mochida, Penner, Pierre N.E. De Graan, Poulain, Simpson, Stecher, Stecher, Stecher, Ulrich Weller, Weller, Weller, Willem-Hendrik Gispen   +35 more
core   +2 more sources