Results 41 to 50 of about 398,844 (320)

Charged Hydrogenic, Helium and Helium-Hydrogenic Molecular Chains in a Strong Magnetic Field [PDF]

open access: yesPhys Rev A 81 (2010) 042503, 2009
A non-relativistic classification of charged molecular hydrogenic, helium and mixed helium-hydrogenic chains with one or two electrons which can exist in a strong magnetic field $B \lesssim 10^{16} $G is given. It is shown that for both $1e-2e$ cases at the strongest studied magnetic fields the longest hydrogenic chain contains at most five protons ...
arxiv   +1 more source

Strict Kantorovich contractions for Markov chains and Euler schemes with general noise [PDF]

open access: yesarXiv, 2021
We study contractions of Markov chains on general metric spaces with respect to some carefully designed distance-like functions, which are comparable to the total variation and the standard $L^p$-Wasserstein distances for $p \ge 1$. We present explicit lower bounds of the corresponding contraction rates.
arxiv  

Immunoglobulin heavy chains in medaka (Oryzias latipes) [PDF]

open access: yesBMC Evolutionary Biology, 2011
Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication of whole genome sequences and the availability of several cDNA libraries for medaka (Oryzias latipes) permitted us to perform a thorough analysis
Magadán-Mompó, S. (Susana)   +2 more
openaire   +7 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]

open access: yesPLoS ONE, 2014
Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta   +4 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Anomalous threshold behavior of long range random walks [PDF]

open access: yesElectron. J. Probab. 20 (2015), no. 74, 1-21, 2014
We consider weighted graphs satisfying sub-Gaussian estimate for the natural random walk. On such graphs, we study symmetric Markov chains with heavy tailed jumps. We establish a threshold behavior of such Markov chains when the index governing the tail heaviness (or jump index) equals the escape time exponent (or walk dimension) of the sub-Gaussian ...
arxiv   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Diversity in the HLA-I Recognition of HLA-F Monoclonal Antibodies: HLA-F or HLA-Ib Monospecific, HLA-E or HLA-G Bispecific Antibodies with or without HLA-Ia Reactivity

open access: yesAntibodies
Previous investigators have used various anti-HLA-F monoclonal antibodies (mAbs) to demonstrate that the tissue distribution of HLA-F is highly restricted. Notably, these mAbs differed in their immunodiagnostic capabilities.
Mepur H. Ravindranath   +4 more
doaj   +1 more source

Significant differences in physicochemical properties of human immunoglobulin kappa and lambda CDR3 regions

open access: yesFrontiers in Immunology, 2016
Antibody variable regions are composed of a heavy and a light chain and in humans there are two light chain isotypes: kappa and lambda. Despite their importance in receptor editing, the light chain is often overlooked in the antibody literature, with the
Catherine L Townsend   +7 more
doaj   +1 more source

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