Results 41 to 50 of about 1,223,101 (358)

Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain

open access: yesBiophysics and Physicobiology, 2023
Ciliary bending movements are powered by motor protein axonemal dyneins. They are largely classified into two groups, inner-arm dynein and outer-arm dynein. Outer-arm dynein, which is important for the elevation of ciliary beat frequency, has three heavy
Toshiki Yagi   +3 more
doaj   +1 more source

Prdm1 (Blimp-1) and the Expression of Fast and Slow Myosin Heavy Chain Isoforms during Avian Myogenesis In Vitro [PDF]

open access: yes, 2010
BACKGROUND. Multiple types of fast and slow skeletal muscle fibers form during early embryogenesis in vertebrates. In zebrafish, formation of the earliest slow myofibers in fin muscles requires expression of the zinc-finger transcriptional repressor ...
Ardelt, Magdalena   +3 more
core   +4 more sources

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

open access: yesFrontiers in Immunology, 2018
We created a novel transgenic rat that expresses human antibodies comprising a diverse repertoire of heavy chains with a single common rearranged kappa light chain (IgKV3-15-JK1).
Katherine E. Harris   +21 more
doaj   +1 more source

Antibodies in a Heavy Chain Knock-In Mouse Exhibit Characteristics of Early Heavy Chain Rearrangement [PDF]

open access: yesThe Journal of Immunology, 2009
Abstract Studies in autoantibody transgenic mice have demonstrated receptor editing rearrangements at Ab H and L chain loci. However, the physiologic role of H chain editing (VH replacement and rearrangement on the second allele) has been called into question.
Wenzhao Meng   +4 more
openaire   +2 more sources

Sudden chain energy transfer events in vibrated granular media [PDF]

open access: yesPhysical Review Letters 106, 088001 (2011), 2011
In a mixture of two species of grains of equal size but different mass, placed in a vertically vibrated shallow box, there is spontaneous segregation. Once the system is at least partly segregated and clusters of the heavy particles have formed, there are sudden peaks of the horizontal kinetic energy of the heavy particles, that is otherwise small ...
arxiv   +1 more source

AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis

open access: yesBMC Nephrology, 2018
Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe   +6 more
doaj   +1 more source

Pinning Model with Heavy Tailed Disorder [PDF]

open access: yesStochastic Process. Appl., 2016, vol. 126, 542-571, 2014
We study the so-called pinning model, which describes the behavior of a Markov chain interacting with a distinguished state. The interaction depends on an external source of randomness, called disorder, which can attract or repel the Markov chain path. We focus on the case when the disorder is heavy-tailed, with infinite mean, while the return times of
arxiv   +1 more source

Immune subtraction for improved resolution in serum protein immunofixation electrophoresis and antibody isotype determination in a patient with autoantibody

open access: yesPractical Laboratory Medicine, 2021
Heavy chain isotypes of low level monoclonal immunoglobulins are sometimes obscured in serum immunofixation electrophoresis (SIFE) by a heavy background of polyclonal immunoglobulins.
Asad Ullah   +4 more
doaj  

Strict Kantorovich contractions for Markov chains and Euler schemes with general noise [PDF]

open access: yesarXiv, 2021
We study contractions of Markov chains on general metric spaces with respect to some carefully designed distance-like functions, which are comparable to the total variation and the standard $L^p$-Wasserstein distances for $p \ge 1$. We present explicit lower bounds of the corresponding contraction rates.
arxiv  

Charged Hydrogenic, Helium and Helium-Hydrogenic Molecular Chains in a Strong Magnetic Field [PDF]

open access: yesPhys Rev A 81 (2010) 042503, 2009
A non-relativistic classification of charged molecular hydrogenic, helium and mixed helium-hydrogenic chains with one or two electrons which can exist in a strong magnetic field $B \lesssim 10^{16} $G is given. It is shown that for both $1e-2e$ cases at the strongest studied magnetic fields the longest hydrogenic chain contains at most five protons ...
arxiv   +1 more source

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