Results 41 to 50 of about 1,130,735 (339)
Partially functional outer arm dynein in a novel Chlamydomonas mutant expressing a truncated γ heavy chain [PDF]
, 2008 The outer dynein arm of Chlamydomonas flagella contains three heavy chains (α, β, and γ), each of which exhibits motor activity. How they assemble and cooperate is of considerable interest.
Kamiya Ritsu +7 more
core +2 more sources
Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]
, 1992 To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD +6 more
core
Immunoglobulin heavy chains in medaka (Oryzias latipes) [PDF]
BMC Evolutionary Biology, 2011 Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication of whole genome sequences and the availability of several cDNA libraries for medaka (Oryzias latipes) permitted us to perform a thorough analysis
Magadán-Mompó, S. (Susana) +2 more
openaire +7 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]
PLoS ONE, 2014 Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta +4 more
doaj +1 more source
Whirling of a heavy chain [PDF]
, 1958 Approximate solutions are obtained for the non-linear problem of the forced whirling of a heavy chain. It is shown that for a given mode of whirling, triple valued solutions are obtained for speeds of rotation above the linear critical speed for that ...
Caughey, T. K.
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
On the stability of rotating heavy chains
Journal of Differential Equations, 1979 AbstractThe object of this paper is two-fold. On the one hand we want to develop the duality theory for critical points which is introduced in [4]. The main result in this context is that if two critical points are in duality, and one of them is a local minimiser of its functional, then so is the other.
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
AntibodiesPrevious investigators have used various anti-HLA-F monoclonal antibodies (mAbs) to demonstrate that the tissue distribution of HLA-F is highly restricted. Notably, these mAbs differed in their immunodiagnostic capabilities.
Mepur H. Ravindranath +4 more
doaj +1 more source