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Zero-state Coupled Markov Switching Count Models for Spatio-temporal Infectious Disease Spread [PDF]

open access: yesJournal of the Royal Statistical Society: Series C (Applied Statistics) (2022) 1-24, Early View, 2021
Spatio-temporal counts of infectious disease cases often contain an excess of zeros. With existing zero inflated count models applied to such data it is difficult to quantify space-time heterogeneity in the effects of disease spread between areas. Also, existing methods do not allow for separate dynamics to affect the reemergence and persistence of the
arxiv   +1 more source

Disease X vaccine production and supply chains: risk assessing healthcare systems operating with artificial intelligence and industry 4.0 [PDF]

open access: yes, 2023
A set of six algorithmic solutions is presented for resolving vaccine production and supply chain bottlenecks. A different set of algorithmic solutions is presented for forecasting risks during a Disease X event.
arxiv   +1 more source

Further studies on an eleventh case of heavy (Hgamma1) chain disease--biosynthetic studies [PDF]

open access: yes, 1975
In vitro quantitative biosynthetic studies were carried out on bone marrow cells obtained from an eleventh case with gamma heavy chain disease. The findings indicate that neither cytoplasmic nor extracellular degradation was responsible for the presence ...
Arima, Terukatsu   +7 more
core   +1 more source

The new Global Multiple Sclerosis Severity Score (MSSS) correlates with axonal but not glial biomarkers [PDF]

open access: yes, 2006
This study investigated whether the new Global Multiple Sclerosis Severity Scale (MSSS) correlated with cerebrospinal fluid biomarkers for axonal and glial pathology.
Eikelenboom, M.J.   +6 more
core   +1 more source

Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein [PDF]

open access: yes, 1995
Background: Heavy-chain diseases (HCDs) are human lymphoproliferative neoplasias that are characterized by the secretion of truncated immunoglobulin heavy chains devoid of light chains.
Bucchini, Danielle   +6 more
core   +1 more source

Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]

open access: yes, 2010
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana   +6 more
core   +1 more source

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