Gamma heavy chain disease complicated by pulmonary hypertension, which was successfully treated with lenalidomide. [PDF]
Shibata S, Fukunaga A.
europepmc +3 more sources
Two Cases of γ-Heavy Chain Disease and a Review of the Literature. [PDF]
Ramasamy I, Rudzki Z.
europepmc +3 more sources
Gamma heavy-chain disease accompanied with follicular lymphoma: a case report. [PDF]
San-José P+4 more
europepmc +3 more sources
T cell receptor rearrangements in a patient with γ-heavy chain disease: A case report. [PDF]
Zhou H+5 more
europepmc +3 more sources
Zero-state Coupled Markov Switching Count Models for Spatio-temporal Infectious Disease Spread [PDF]
Spatio-temporal counts of infectious disease cases often contain an excess of zeros. With existing zero inflated count models applied to such data it is difficult to quantify space-time heterogeneity in the effects of disease spread between areas. Also, existing methods do not allow for separate dynamics to affect the reemergence and persistence of the
arxiv +1 more source
Disease X vaccine production and supply chains: risk assessing healthcare systems operating with artificial intelligence and industry 4.0 [PDF]
A set of six algorithmic solutions is presented for resolving vaccine production and supply chain bottlenecks. A different set of algorithmic solutions is presented for forecasting risks during a Disease X event.
arxiv +1 more source
Further studies on an eleventh case of heavy (Hgamma1) chain disease--biosynthetic studies [PDF]
In vitro quantitative biosynthetic studies were carried out on bone marrow cells obtained from an eleventh case with gamma heavy chain disease. The findings indicate that neither cytoplasmic nor extracellular degradation was responsible for the presence ...
Arima, Terukatsu+7 more
core +1 more source
The new Global Multiple Sclerosis Severity Score (MSSS) correlates with axonal but not glial biomarkers [PDF]
This study investigated whether the new Global Multiple Sclerosis Severity Scale (MSSS) correlated with cerebrospinal fluid biomarkers for axonal and glial pathology.
Eikelenboom, M.J.+6 more
core +1 more source
Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein [PDF]
Background: Heavy-chain diseases (HCDs) are human lymphoproliferative neoplasias that are characterized by the secretion of truncated immunoglobulin heavy chains devoid of light chains.
Bucchini, Danielle+6 more
core +1 more source
Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana+6 more
core +1 more source