Clec9a-mediated ablation of conventional dendritic cells suggests a lymphoid path to generating dendritic cells In Vivo [PDF]
, 2018 Conventional dendritic cells (cDCs) are versatile activators of immune responses that develop as part of the myeloid lineage downstream of hematopoietic stem cells.
Keppler, SJ +10 more
core +1 more source
Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B. [PDF]
PLoS ONE, 2016 Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of the ...
Sebastian Miethe +13 more
doaj +1 more source
Medicines, 2023 Background: Monoclonal immunoglobulin deposition disease (MIDD) includes three entities: light chain deposition disease (LCDD), heavy chain deposition disease (HCDD) and light and heavy chain deposition disease (LHCDD).
José C. De La Flor +10 more
doaj +1 more source
The antibody loci of the domestic goat (Capra hircus) [PDF]
, 2018 The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M. +4 more
core +1 more source
Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives
Neural Regeneration Research, 2021 Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons.
Yuri Matteo Falzone +6 more
doaj +1 more source
IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications [PDF]
, 2019 The precise B cell of origin and molecular pathogenesis of nodal marginal zone lymphoma (NMZL) remain poorly defined. To date, due to the rarity of NMZL, the vast majority of already-published studies have been conducted on a limited number of samples ...
Amato, Teresa +15 more
core +2 more sources
Fibre types in skeletal muscles of chronic obstructive pulmonary disease patients related to respiratory function and exercise tolerance. [PDF]
, 1997 This study aimed to investigate the relationship between skeletal muscle, fibre type composition, functional respiratory impairment and exercise tolerance in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
Bottinelli, R +7 more
core +1 more source
Hypertension, renal failure, and edema in a 38-year-old man: light chain deposition disease; a case report and review of the literature [PDF]
Journal of Nephropathology, 2014 Background: Monoclonal immunoglobulin deposition disease (MIDD) is a rare disease, usually manifesting between the 5th and 6th decades of life but can also occur earlier. Characteristic feature of MIDD is a non-fibrillar, Congo red negative deposition of
Sarmad Said +4 more
doaj +1 more source
Case Reports in Oncology, 2021 We present a case report of a 62-year-old male, treated for kappa light chain multiple myeloma with chemotherapy followed by autologous stem cell transplant (ASCT) in 2014. He has been in complete remission for 4 years.
Sowmya Thanikachalam +4 more
doaj +1 more source
BMC Nephrology, 2018 Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe +6 more
doaj +1 more source