Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum [PDF]
BackgroundAmphibians are valuable models for comparative immunology. In the caudate Ambystoma mexicanum, the architecture of immunoglobulin loci resembles that of the anuran Xenopus tropicalis, although some antibody gene features are absent.
Diana L. Pacheco-Olvera +9 more
doaj +2 more sources
Avian Resistance to Campylobacter jejuni Colonization Is Associated with an Intestinal Immunogene Expression Signature Identified by mRNA Sequencing [PDF]
peer-reviewedThis research was funded by the The Irish Department of Agriculture and Food’s Food Institutional Research Measure (http://www.agriculture.gov.ie/ research/foodinstitutionalresearchmeasurefirm) – Grant No: 06_RDD_486.Campylobacter jejuni is
Allan, Brenda +8 more
core +11 more sources
Background: Abnormal plasma cells in multiple myeloma produce excessive amounts of immunoglobulins and free light chains, of which certain patterns predict patient survival.
Ifeyinwa D Nnakenyi +6 more
doaj +1 more source
How Different Snacks Produce a Distinct Effect in Salivary Protein Composition
Saliva secretion changes in response to different stimulation. Studies performed in animals and humans suggest that dietary constituents may influence saliva composition, although the dynamics of these changes, and how they are specific for each type of ...
Carla Simões +4 more
doaj +1 more source
Alpha Toxin Purification and Antibody Production Against Local Strain of Clostridium septicum NH2 [PDF]
BACKGROUND: Clostridium septicum has played a significant role as a causative agent of many acute fetal diseases in man and animals. Alpha- toxin is the main factor in the pathogenesis of C.
Mohsen Najafi Najafi +2 more
doaj +1 more source
Complete amino acid sequence of a mouse immunoglobulin alpha chain (MOPC 511). [PDF]
The complete amino acid sequence of the 432-residue heavy (alpha) chain of mouse myeloma MOPC 511 has been determined. The variable region of the alpha chain of IgA 511, a phosphocholine-binding protein, is highly homologous to that of the other phosphocholine-binding immunoglobulins. Comparison of the 511 alpha chain constant region with that of other
E A, Robinson, E, Appella
openaire +2 more sources
In the mammalian immune system, the surrogate light chain (SLC) shapes the antibody repertoire during B cell development by serving as a checkpoint for production of functional heavy chains (HC).
Jeannine A. Ott +7 more
doaj +1 more source
“Alpha Chain Disease” Protein Def: Internal Deletion of a Human Immunoglobulin A 1 Heavy Chain [PDF]
Protein Def is a human alpha chain disease protein related to α1 immunoglobulin heavy chain. The molecular weight of the polypeptide portion of the monomeric molecule is 29,300, which is a little greater than half of a normal α1 chain. The NH 2 -terminal of the polypeptide is heterogenous and, after a short segment ...
C, Wolfenstein-Todel +2 more
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Intraspecies heterogeneity of immunoglobulin α‐chain constant region genes in rhesus macaques [PDF]
SummaryImmunoglobulin A (IgA) is the major antibody class present in external secretions and is also an important component of serum immunoglobulins. On mucosal surfaces, IgA represents a first line of defence by neutralizing invading pathogens.
F, Scinicariello, R, Attanasio
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Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products. [PDF]
We have cloned and determined the entire nucleotide sequence of cDNAs corresponding to the putative alpha subunits of the human and rat mast cell high-affinity IgE receptors. Both human and rat cDNAs encode an NH2-terminal signal peptide, two immunoglobulin-like extracellular domains (encoded by discrete exons), a hydrophobic transmembrane region, and ...
A, Shimizu +5 more
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